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The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection.
Richards CM, Jabs S, Qiao W, Varanese LD, Schweizer M, Mosen PR, Riley NM, Klüssendorf M, Zengel JR, Flynn RA, Rustagi A, Widen JC, Peters CE, Ooi YS, Xie X, Shi PY, Bartenschlager R, Puschnik AS, Bogyo M, Bertozzi CR, Blish CA, Winter D, Nagamine CM, Braulke T, Carette JE. Richards CM, et al. Among authors: blish ca. Science. 2022 Oct 7;378(6615):eabn5648. doi: 10.1126/science.abn5648. Epub 2022 Oct 7. Science. 2022. PMID: 36074821 Free PMC article.
Disease diagnostics using machine learning of immune receptors.
Zaslavsky ME, Craig E, Michuda JK, Sehgal N, Ram-Mohan N, Lee JY, Nguyen KD, Hoh RA, Pham TD, Röltgen K, Lam B, Parsons ES, Macwana SR, DeJager W, Drapeau EM, Roskin KM, Cunningham-Rundles C, Moody MA, Haynes BF, Goldman JD, Heath JR, Nadeau KC, Pinsky BA, Blish CA, Hensley SE, Jensen K, Meyer E, Balboni I, Utz PJ, Merrill JT, Guthridge JM, James JA, Yang S, Tibshirani R, Kundaje A, Boyd SD. Zaslavsky ME, et al. Among authors: blish ca. bioRxiv [Preprint]. 2024 Apr 3:2022.04.26.489314. doi: 10.1101/2022.04.26.489314. bioRxiv. 2024. PMID: 35547855 Free PMC article. Preprint.
A single-cell atlas of the peripheral immune response in patients with severe COVID-19.
Wilk AJ, Rustagi A, Zhao NQ, Roque J, Martínez-Colón GJ, McKechnie JL, Ivison GT, Ranganath T, Vergara R, Hollis T, Simpson LJ, Grant P, Subramanian A, Rogers AJ, Blish CA. Wilk AJ, et al. Among authors: blish ca. Nat Med. 2020 Jul;26(7):1070-1076. doi: 10.1038/s41591-020-0944-y. Epub 2020 Jun 8. Nat Med. 2020. PMID: 32514174 Free PMC article.
B cell clonal expansion and convergent antibody responses to SARS-CoV-2.
Nielsen SCA, Yang F, Hoh RA, Jackson KJL, Roeltgen K, Lee JY, Rustagi A, Rogers AJ, Powell AE, Kim PS, Wang TT, Pinsky B, Blish CA, Boyd SD. Nielsen SCA, et al. Among authors: blish ca. Res Sq [Preprint]. 2020 May 6:rs.3.rs-27220. doi: 10.21203/rs.3.rs-27220/v1. Res Sq. 2020. PMID: 32702737 Free PMC article. Updated. Preprint.
Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2.
Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Röltgen K, Jean GH, Stevens BA, Lee JY, Rustagi A, Rogers AJ, Powell AE, Hunter M, Najeeb J, Otrelo-Cardoso AR, Yost KE, Daniel B, Nadeau KC, Chang HY, Satpathy AT, Jardetzky TS, Kim PS, Wang TT, Pinsky BA, Blish CA, Boyd SD. Nielsen SCA, et al. Among authors: blish ca. Cell Host Microbe. 2020 Oct 7;28(4):516-525.e5. doi: 10.1016/j.chom.2020.09.002. Epub 2020 Sep 3. Cell Host Microbe. 2020. PMID: 32941787 Free PMC article.
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids.
Salahudeen AA, Choi SS, Rustagi A, Zhu J, van Unen V, de la O SM, Flynn RA, Margalef-Català M, Santos AJM, Ju J, Batish A, Usui T, Zheng GXY, Edwards CE, Wagar LE, Luca V, Anchang B, Nagendran M, Nguyen K, Hart DJ, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Harbury PB, Glenn JS, Garcia KC, Davis MM, Baric RS, Sabatti C, Amieva MR, Blish CA, Desai TJ, Kuo CJ. Salahudeen AA, et al. Among authors: blish ca. Nature. 2020 Dec;588(7839):670-675. doi: 10.1038/s41586-020-3014-1. Epub 2020 Nov 25. Nature. 2020. PMID: 33238290 Free PMC article.
Profiling of the Human Natural Killer Cell Receptor-Ligand Repertoire.
Vendrame E, McKechnie JL, Ranganath T, Zhao NQ, Rustagi A, Vergara R, Ivison GT, Kronstad LM, Simpson LJ, Blish CA. Vendrame E, et al. Among authors: blish ca. J Vis Exp. 2020 Nov 19;(165):10.3791/61912. doi: 10.3791/61912. J Vis Exp. 2020. PMID: 33283785 Free PMC article.
Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome.
Röltgen K, Powell AE, Wirz OF, Stevens BA, Hogan CA, Najeeb J, Hunter M, Wang H, Sahoo MK, Huang C, Yamamoto F, Manohar M, Manalac J, Otrelo-Cardoso AR, Pham TD, Rustagi A, Rogers AJ, Shah NH, Blish CA, Cochran JR, Jardetzky TS, Zehnder JL, Wang TT, Narasimhan B, Gombar S, Tibshirani R, Nadeau KC, Kim PS, Pinsky BA, Boyd SD. Röltgen K, et al. Among authors: blish ca. Sci Immunol. 2020 Dec 7;5(54):eabe0240. doi: 10.1126/sciimmunol.abe0240. Sci Immunol. 2020. PMID: 33288645 Free PMC article.
Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19.
Delaveris CS, Wilk AJ, Riley NM, Stark JC, Yang SS, Rogers AJ, Ranganath T, Nadeau KC; Stanford COVID-19 Biobank; Blish CA, Bertozzi CR. Delaveris CS, et al. Among authors: blish ca. ACS Cent Sci. 2021 Apr 28;7(4):650-657. doi: 10.1021/acscentsci.0c01669. Epub 2021 Mar 24. ACS Cent Sci. 2021. PMID: 34056095 Free PMC article.
SARS-CoV-2 Subgenomic RNA Kinetics in Longitudinal Clinical Samples.
Verma R, Kim E, Martínez-Colón GJ, Jagannathan P, Rustagi A, Parsonnet J, Bonilla H, Khosla C, Holubar M, Subramanian A, Singh U, Maldonado Y, Blish CA, Andrews JR. Verma R, et al. Among authors: blish ca. Open Forum Infect Dis. 2021 Jun 11;8(7):ofab310. doi: 10.1093/ofid/ofab310. eCollection 2021 Jul. Open Forum Infect Dis. 2021. PMID: 34295944 Free PMC article.
138 results