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Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.
Monn JA, Prieto L, Taboada L, Pedregal C, Hao J, Reinhard MR, Henry SS, Goldsmith PJ, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, Marcos A, Blanco J, Bures M, Clawson DK, Atwell S, Lu F, Wang J, Russell M, Heinz BA, Wang X, Carter JH, Xiang C, Catlow JT, Swanson S, Sanger H, Broad LM, Johnson MP, Knopp KL, Simmons RM, Johnson BG, Shaw DB, McKinzie DL. Monn JA, et al. Among authors: blanco j. J Med Chem. 2015 Feb 26;58(4):1776-94. doi: 10.1021/jm501612y. Epub 2015 Feb 5. J Med Chem. 2015. PMID: 25602126
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist.
Monn JA, Prieto L, Taboada L, Hao J, Reinhard MR, Henry SS, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, Marcos A, Blanco J, Bures M, Clawson DK, Atwell S, Lu F, Wang J, Russell M, Heinz BA, Wang X, Carter JH, Getman BG, Catlow JT, Swanson S, Johnson BG, Shaw DB, McKinzie DL. Monn JA, et al. Among authors: blanco j. J Med Chem. 2015 Sep 24;58(18):7526-48. doi: 10.1021/acs.jmedchem.5b01124. J Med Chem. 2015. PMID: 26313429
SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes.
Sabadell-Basallote J, Astiarraga B, Castaño C, Ejarque M, Repollés-de-Dalmau M, Quesada I, Blanco J, Nuñez-Roa C, Rodríguez-Peña MM, Martínez L, De Jesus DF, Marroqui L, Bosch R, Montanya E, Sureda FX, Tura A, Mari A, Kulkarni RN, Vendrell J, Fernández-Veledo S. Sabadell-Basallote J, et al. Among authors: blanco j. J Clin Invest. 2024 May 7:e173214. doi: 10.1172/JCI173214. Online ahead of print. J Clin Invest. 2024. PMID: 38713514 Free article.
Differences in clinical outcomes of bloodstream infections caused by Klebsiella aerogenes, Klebsiella pneumoniae and Enterobacter cloacae: a multicentre cohort study.
Guedes M, Gathara D, López-Hernández I, Pérez-Crespo PMM, Pérez-Rodríguez MT, Sousa A, Plata A, Reguera-Iglesias JM, Boix-Palop L, Dietl B, Blanco JS, Castillo CA, Galán-Sánchez F, Kindelán CN, Jover-Saenz A, Aguirre JG, Alemán AA, Ciordia TM, Del Arco Jiménez A, Fernandez-Suarez J, Lopez-Cortes LE, Rodríguez-Baño J; PROBAC/GEIRAS-SEIMC/SAMICEI group. Guedes M, et al. Among authors: blanco js. Ann Clin Microbiol Antimicrob. 2024 May 6;23(1):42. doi: 10.1186/s12941-024-00700-8. Ann Clin Microbiol Antimicrob. 2024. PMID: 38711045 Free PMC article.
The Longitudinal Effects of Posterior Spinal Fusion with Derotation on Axial Deformity in Adolescent Idiopathic Scoliosis.
Linden GS, Adhiyaman A, Zucker CP, Thakur A, Wisch JL, Hillstrom H, Groisser BN, Mintz DN, Cunningham ME, Haddas R, Hresko MT, Blanco JS, Widmann RF, Heyer JH. Linden GS, et al. Among authors: blanco js. Spine (Phila Pa 1976). 2024 May 6. doi: 10.1097/BRS.0000000000005021. Online ahead of print. Spine (Phila Pa 1976). 2024. PMID: 38709012
How appropriate is treating patients diagnosed with advanced esophageal cancer with anticancer drugs? A multicenter retrospective cohort Spanish study.
Santero M, Requeijo C, Quintana MJ, Rodríguez D, Bottaro D, Macias I, Pericay C, Farina N, Blanco JM, Urreta-Barallobre I, Punti L, Nava MA, Bonfill Cosp X. Santero M, et al. Among authors: blanco jm. Clin Transl Oncol. 2024 Apr 25. doi: 10.1007/s12094-024-03436-1. Online ahead of print. Clin Transl Oncol. 2024. PMID: 38662169
CoaguChek and Coag-Sense PT2 Meter Point of Care INR Device Validation.
McBane RD 2nd, O'Connor C, Lutz J, Blanco J, Hartman LA, Kramer A, Uy J, Schumann T, Hartung K, Luker M, Hodge D, Santrach P, Karon BS. McBane RD 2nd, et al. Among authors: blanco j. Mayo Clin Proc. 2024 Apr 24:S0025-6196(23)00476-7. doi: 10.1016/j.mayocp.2023.10.006. Online ahead of print. Mayo Clin Proc. 2024. PMID: 38661594
2,640 results