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Page 1
Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.
Gauttier V, Pengam S, Durand J, Biteau K, Mary C, Morello A, Néel M, Porto G, Teppaz G, Thepenier V, Danger R, Vince N, Wilhelm E, Girault I, Abes R, Ruiz C, Trilleaud C, Ralph K, Trombetta ES, Garcia A, Vignard V, Martinet B, Glémain A, Bruneau S, Haspot F, Dehmani S, Duplouye P, Miyasaka M, Labarrière N, Laplaud D, Le Bas-Bernardet S, Blanquart C, Catros V, Gouraud PA, Archambeaud I, Aublé H, Metairie S, Mosnier JF, Costantini D, Blancho G, Conchon S, Vanhove B, Poirier N. Gauttier V, et al. Among authors: blancho g. J Clin Invest. 2020 Nov 2;130(11):6109-6123. doi: 10.1172/JCI135528. J Clin Invest. 2020. PMID: 33074246 Free PMC article.
Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation.
Poirier N, Azimzadeh AM, Zhang T, Dilek N, Mary C, Nguyen B, Tillou X, Wu G, Reneaudin K, Hervouet J, Martinet B, Coulon F, Allain-Launay E, Karam G, Soulillou JP, Pierson RN 3rd, Blancho G, Vanhove B. Poirier N, et al. Among authors: blancho g. Sci Transl Med. 2010 Feb 3;2(17):17ra10. doi: 10.1126/scitranslmed.3000116. Sci Transl Med. 2010. PMID: 20371478 Free PMC article.
A more selective costimulatory blockade of the CD28-B7 pathway.
Poirier N, Blancho G, Vanhove B. Poirier N, et al. Among authors: blancho g. Transpl Int. 2011 Jan;24(1):2-11. doi: 10.1111/j.1432-2277.2010.01176.x. Epub 2010 Oct 21. Transpl Int. 2011. PMID: 20964725 Free article. Review.
Antibody-mediated depletion of lymphocyte-activation gene-3 (LAG-3(+) )-activated T lymphocytes prevents delayed-type hypersensitivity in non-human primates.
Poirier N, Haudebourg T, Brignone C, Dilek N, Hervouet J, Minault D, Coulon F, de Silly RV, Triebel F, Blancho G, Vanhove B. Poirier N, et al. Among authors: blancho g. Clin Exp Immunol. 2011 May;164(2):265-74. doi: 10.1111/j.1365-2249.2011.04329.x. Epub 2011 Feb 24. Clin Exp Immunol. 2011. PMID: 21352204 Free PMC article.
Xenotransplantation of galactosyl-transferase knockout, CD55, CD59, CD39, and fucosyl-transferase transgenic pig kidneys into baboons.
Le Bas-Bernardet S, Tillou X, Poirier N, Dilek N, Chatelais M, Devallière J, Charreau B, Minault D, Hervouet J, Renaudin K, Crossan C, Scobie L, Cowan PJ, d'Apice AJ, Galli C, Cozzi E, Soulillou JP, Vanhove B, Blancho G. Le Bas-Bernardet S, et al. Among authors: blancho g. Transplant Proc. 2011 Nov;43(9):3426-30. doi: 10.1016/j.transproceed.2011.09.024. Transplant Proc. 2011. PMID: 22099813
Transplant tolerance is associated with reduced expression of cystathionine-γ-lyase that controls IL-12 production by dendritic cells and TH-1 immune responses.
Vuillefroy de Silly R, Coulon F, Poirier N, Jovanovic V, Brouard S, Ferchaud-Roucher V, Blancho G, Vanhove B. Vuillefroy de Silly R, et al. Among authors: blancho g. Blood. 2012 Mar 15;119(11):2633-43. doi: 10.1182/blood-2011-04-350546. Epub 2012 Jan 19. Blood. 2012. PMID: 22262763 Free article.
205 results