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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism.
Vaseva AV, Blake DR, Gilbert TSK, Ng S, Hostetter G, Azam SH, Ozkan-Dagliyan I, Gautam P, Bryant KL, Pearce KH, Herring LE, Han H, Graves LM, Witkiewicz AK, Knudsen ES, Pecot CV, Rashid N, Houghton PJ, Wennerberg K, Cox AD, Der CJ. Vaseva AV, et al. Among authors: blake dr. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. doi: 10.1016/j.ccell.2018.10.001. Cancer Cell. 2018. PMID: 30423298 Free PMC article.
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N, Tanaseichuk O, Chen K, Zhou Y, Kalkat M, Herring LE, Graves LM, Penn LZ, Yin HH, Aguirre AJ, Hahn WC, Cox AD, Der CJ. Waters AM, et al. Among authors: blake dr. Cell Rep. 2021 Jun 29;35(13):109291. doi: 10.1016/j.celrep.2021.109291. Cell Rep. 2021. PMID: 34192548 Free PMC article.
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
Diehl JN, Klomp JE, Snare KR, Hibshman PS, Blake DR, Kaiser ZD, Gilbert TSK, Baldelli E, Pierobon M, Papke B, Yang R, Hodge RG, Rashid NU, Petricoin EF 3rd, Herring LE, Graves LM, Cox AD, Der CJ. Diehl JN, et al. Among authors: blake dr. J Biol Chem. 2021 Nov;297(5):101335. doi: 10.1016/j.jbc.2021.101335. Epub 2021 Oct 22. J Biol Chem. 2021. PMID: 34688654 Free PMC article.
Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.
Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ. Zhang H, et al. Among authors: blake dr. Cancer Discov. 2020 Feb;10(2):288-305. doi: 10.1158/2159-8290.CD-19-0811. Epub 2019 Nov 26. Cancer Discov. 2020. PMID: 31771969 Free PMC article.
Lamellipodia are crucial for haptotactic sensing and response.
King SJ, Asokan SB, Haynes EM, Zimmerman SP, Rotty JD, Alb JG Jr, Tagliatela A, Blake DR, Lebedeva IP, Marston D, Johnson HE, Parsons M, Sharpless NE, Kuhlman B, Haugh JM, Bear JE. King SJ, et al. Among authors: blake dr. J Cell Sci. 2016 Jun 15;129(12):2329-42. doi: 10.1242/jcs.184507. Epub 2016 May 12. J Cell Sci. 2016. PMID: 27173494 Free PMC article.
Unrecognized volatile and semi-volatile organic compounds from brake wear.
Perraud V, Blake DR, Wingen LM, Barletta B, Bauer PS, Campos J, Ezell MJ, Guenther A, Johnson KN, Lee M, Meinardi S, Patterson J, Saltzman ES, Thomas AE, Smith JN, Finlayson-Pitts BJ. Perraud V, et al. Among authors: blake dr. Environ Sci Process Impacts. 2024 Apr 18. doi: 10.1039/d4em00024b. Online ahead of print. Environ Sci Process Impacts. 2024. PMID: 38635247
Hydrocarbon Tracers Suggest Methane Emissions from Fossil Sources Occur Predominately Before Gas Processing and That Petroleum Plays Are a Significant Source.
Tribby AL, Bois JS, Montzka SA, Atlas EL, Vimont I, Lan X, Tans PP, Elkins JW, Blake DR, Wennberg PO. Tribby AL, et al. Among authors: blake dr. Environ Sci Technol. 2022 Jul 5;56(13):9623-9631. doi: 10.1021/acs.est.2c00927. Epub 2022 Jun 14. Environ Sci Technol. 2022. PMID: 35699285 Free PMC article.
Contribution of Organic Nitrates to Organic Aerosol over South Korea during KORUS-AQ.
Kenagy HS, Romer Present PS, Wooldridge PJ, Nault BA, Campuzano-Jost P, Day DA, Jimenez JL, Zare A, Pye HOT, Yu J, Song CH, Blake DR, Woo JH, Kim Y, Cohen RC. Kenagy HS, et al. Among authors: blake dr. Environ Sci Technol. 2021 Dec 21;55(24):16326-16338. doi: 10.1021/acs.est.1c05521. Epub 2021 Dec 6. Environ Sci Technol. 2021. PMID: 34870986 Free PMC article.
Rapid cloud removal of dimethyl sulfide oxidation products limits SO2 and cloud condensation nuclei production in the marine atmosphere.
Novak GA, Fite CH, Holmes CD, Veres PR, Neuman JA, Faloona I, Thornton JA, Wolfe GM, Vermeuel MP, Jernigan CM, Peischl J, Ryerson TB, Thompson CR, Bourgeois I, Warneke C, Gkatzelis GI, Coggon MM, Sekimoto K, Bui TP, Dean-Day J, Diskin GS, DiGangi JP, Nowak JB, Moore RH, Wiggins EB, Winstead EL, Robinson C, Thornhill KL, Sanchez KJ, Hall SR, Ullmann K, Dollner M, Weinzierl B, Blake DR, Bertram TH. Novak GA, et al. Among authors: blake dr. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2110472118. doi: 10.1073/pnas.2110472118. Proc Natl Acad Sci U S A. 2021. PMID: 34635596 Free PMC article.
438 results