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Stress biology: Complexity and multifariousness in health and disease.
Mayer MP, Blair L, Blatch GL, Borges TJ, Chadli A, Chiosis G, de Thonel A, Dinkova-Kostova A, Ecroyd H, Edkins AL, Eguchi T, Fleshner M, Foley KP, Fragkostefanakis S, Gestwicki J, Goloubinoff P, Heritz JA, Heske CM, Hibshman JD, Joutsen J, Li W, Lynes M, Mendillo ML, Mivechi N, Mokoena F, Okusha Y, Prahlad V, Repasky E, Sannino S, Scalia F, Shalgi R, Sistonen L, Sontag E, van Oosten-Hawle P, Vihervaara A, Wickramaratne A, Wang SXY, Zininga T. Mayer MP, et al. Among authors: blair l. Cell Stress Chaperones. 2024 Feb;29(1):143-157. doi: 10.1016/j.cstres.2024.01.006. Epub 2024 Feb 3. Cell Stress Chaperones. 2024. PMID: 38311120 Free PMC article.
Editorial: A new chapter for Cell Stress and Chaperones.
Bourboulia D, Blair LJ, Clark MS, Edkins AL, Hightower LE, Mollapour M, Prahlad V, Repasky EA, Truebano M, Truman AW, Truttmann MC, van Oosten-Hawle P, Woodford MR. Bourboulia D, et al. Among authors: blair lj. Cell Stress Chaperones. 2024 Feb;29(1):113-115. doi: 10.1016/j.cstres.2024.01.007. Epub 2024 Feb 1. Cell Stress Chaperones. 2024. PMID: 38309687 Free PMC article. No abstract available.
Facilitating Akt clearance via manipulation of Hsp70 activity and levels.
Koren J 3rd, Jinwal UK, Jin Y, O'Leary J, Jones JR, Johnson AG, Blair LJ, Abisambra JF, Chang L, Miyata Y, Cheng AM, Guo J, Cheng JQ, Gestwicki JE, Dickey CA. Koren J 3rd, et al. Among authors: blair lj. J Biol Chem. 2010 Jan 22;285(4):2498-505. doi: 10.1074/jbc.M109.057208. Epub 2009 Nov 4. J Biol Chem. 2010. PMID: 19889640 Free PMC article.
Hsc70 rapidly engages tau after microtubule destabilization.
Jinwal UK, O'Leary JC 3rd, Borysov SI, Jones JR, Li Q, Koren J 3rd, Abisambra JF, Vestal GD, Lawson LY, Johnson AG, Blair LJ, Jin Y, Miyata Y, Gestwicki JE, Dickey CA. Jinwal UK, et al. J Biol Chem. 2010 May 28;285(22):16798-805. doi: 10.1074/jbc.M110.113753. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308058 Free PMC article.
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Singh JK, Hutt DM, Tait B, Guy NC, Sivils JC, Ortiz NR, Payan AN, Komaragiri SK, Owens JJ, Culbertson D, Blair LJ, Dickey C, Kuo SY, Finley D, Dyson HJ, Cox MB, Chaudhary J, Gestwicki JE, Balch WE. Singh JK, et al. Cell Chem Biol. 2020 Mar 19;27(3):292-305.e6. doi: 10.1016/j.chembiol.2020.01.008. Epub 2020 Feb 3. Cell Chem Biol. 2020. PMID: 32017918 Free PMC article.
Imbalance of Hsp70 family variants fosters tau accumulation.
Jinwal UK, Akoury E, Abisambra JF, O'Leary JC 3rd, Thompson AD, Blair LJ, Jin Y, Bacon J, Nordhues BA, Cockman M, Zhang J, Li P, Zhang B, Borysov S, Uversky VN, Biernat J, Mandelkow E, Gestwicki JE, Zweckstetter M, Dickey CA. Jinwal UK, et al. FASEB J. 2013 Apr;27(4):1450-9. doi: 10.1096/fj.12-220889. Epub 2012 Dec 27. FASEB J. 2013. PMID: 23271055 Free PMC article.
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.
Abisambra J, Jinwal UK, Miyata Y, Rogers J, Blair L, Li X, Seguin SP, Wang L, Jin Y, Bacon J, Brady S, Cockman M, Guidi C, Zhang J, Koren J, Young ZT, Atkins CA, Zhang B, Lawson LY, Weeber EJ, Brodsky JL, Gestwicki JE, Dickey CA. Abisambra J, et al. Among authors: blair l. Biol Psychiatry. 2013 Sep 1;74(5):367-74. doi: 10.1016/j.biopsych.2013.02.027. Epub 2013 Apr 19. Biol Psychiatry. 2013. PMID: 23607970 Free PMC article.
386 results