Blackledge M - Search Results

1

Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP.

Roldan JL, Blackledge M, van Nuland NA, Azuaga AI. Roldan JL, et al. Among authors: blackledge m. J Biomol NMR. 2011 Jun;50(2):103-17. doi: 10.1007/s10858-011-9505-5. Epub 2011 Apr 26. J Biomol NMR. 2011. PMID: 21519904

2

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex.

Ortega-Roldan JL, Jensen MR, Brutscher B, Azuaga AI, Blackledge M, van Nuland NA. Ortega-Roldan JL, et al. Among authors: blackledge m. Nucleic Acids Res. 2009 May;37(9):e70. doi: 10.1093/nar/gkp211. Epub 2009 Apr 9. Nucleic Acids Res. 2009. PMID: 19359362 Free PMC article.

3

Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional implications.

Ortega Roldan JL, Casares S, Ringkjøbing Jensen M, Cárdenes N, Bravo J, Blackledge M, Azuaga AI, van Nuland NA. Ortega Roldan JL, et al. Among authors: blackledge m. PLoS One. 2013 Sep 11;8(9):e73018. doi: 10.1371/journal.pone.0073018. eCollection 2013. PLoS One. 2013. PMID: 24039852 Free PMC article.

4

Multi-timescale conformational dynamics of the SH3 domain of CD2-associated protein using NMR spectroscopy and accelerated molecular dynamics.

Salmon L, Pierce L, Grimm A, Ortega Roldan JL, Mollica L, Jensen MR, van Nuland N, Markwick PR, McCammon JA, Blackledge M. Salmon L, et al. Among authors: blackledge m. Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6103-6. doi: 10.1002/anie.201202026. Epub 2012 May 8. Angew Chem Int Ed Engl. 2012. PMID: 22565613 Free PMC article. No abstract available.

5

Mapping the population of protein conformational energy sub-states from NMR dipolar couplings.

Guerry P, Salmon L, Mollica L, Ortega Roldan JL, Markwick P, van Nuland NA, McCammon JA, Blackledge M. Guerry P, et al. Among authors: blackledge m. Angew Chem Int Ed Engl. 2013 Mar 11;52(11):3181-5. doi: 10.1002/anie.201209669. Epub 2013 Feb 1. Angew Chem Int Ed Engl. 2013. PMID: 23371543 Free article. No abstract available.

6

Structure, dynamics, and kinetics of weak protein-protein complexes from NMR spin relaxation measurements of titrated solutions.

Salmon L, Ortega Roldan JL, Lescop E, Licinio A, van Nuland N, Jensen MR, Blackledge M. Salmon L, et al. Among authors: blackledge m. Angew Chem Int Ed Engl. 2011 Apr 11;50(16):3755-9. doi: 10.1002/anie.201100310. Epub 2011 Mar 18. Angew Chem Int Ed Engl. 2011. PMID: 21425222 No abstract available.

7

Characterizing weak protein-protein complexes by NMR residual dipolar couplings.

Jensen MR, Ortega-Roldan JL, Salmon L, van Nuland N, Blackledge M. Jensen MR, et al. Among authors: blackledge m. Eur Biophys J. 2011 Dec;40(12):1371-81. doi: 10.1007/s00249-011-0720-5. Epub 2011 Jun 28. Eur Biophys J. 2011. PMID: 21710303 Review.

8

Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.

Sterckx YG, Volkov AN, Vranken WF, Kragelj J, Jensen MR, Buts L, Garcia-Pino A, Jové T, Van Melderen L, Blackledge M, van Nuland NA, Loris R. Sterckx YG, et al. Among authors: blackledge m. Structure. 2014 Jun 10;22(6):854-65. doi: 10.1016/j.str.2014.03.012. Epub 2014 Apr 24. Structure. 2014. PMID: 24768114 Free article.

9

Structural dynamics of protein backbone phi angles: extended molecular dynamics simulations versus experimental (3) J scalar couplings.

Markwick PR, Showalter SA, Bouvignies G, Brüschweiler R, Blackledge M. Markwick PR, et al. Among authors: blackledge m. J Biomol NMR. 2009 Sep;45(1-2):17-21. doi: 10.1007/s10858-009-9341-z. Epub 2009 Jul 24. J Biomol NMR. 2009. PMID: 19629714

10

Toward a unified representation of protein structural dynamics in solution.

Markwick PR, Bouvignies G, Salmon L, McCammon JA, Nilges M, Blackledge M. Markwick PR, et al. Among authors: blackledge m. J Am Chem Soc. 2009 Nov 25;131(46):16968-75. doi: 10.1021/ja907476w. J Am Chem Soc. 2009. PMID: 19919148 Free PMC article.

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