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Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability.
Hodson C, Low JKK, van Twest S, Jones SE, Swuec P, Murphy V, Tsukada K, Fawkes M, Bythell-Douglas R, Davies A, Holien JK, O'Rourke JJ, Parker BL, Glaser A, Parker MW, Mackay JP, Blackford AN, Costa A, Deans AJ. Hodson C, et al. Among authors: blackford an. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2109093119. doi: 10.1073/pnas.2109093119. Proc Natl Acad Sci U S A. 2022. PMID: 35115399 Free PMC article.
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M. Leimbacher PA, et al. Among authors: blackford an. Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18. Mol Cell. 2019. PMID: 30898438 Free PMC article.
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.
Groelly FJ, Dagg RA, Petropoulos M, Rossetti GG, Prasad B, Panagopoulos A, Paulsen T, Karamichali A, Jones SE, Ochs F, Dionellis VS, Puig Lombardi E, Miossec MJ, Lockstone H, Legube G, Blackford AN, Altmeyer M, Halazonetis TD, Tarsounas M. Groelly FJ, et al. Among authors: blackford an. Mol Cell. 2022 Sep 15;82(18):3382-3397.e7. doi: 10.1016/j.molcel.2022.07.011. Epub 2022 Aug 23. Mol Cell. 2022. PMID: 36002001 Free PMC article.
Targeting DNA damage response pathways in cancer.
Groelly FJ, Fawkes M, Dagg RA, Blackford AN, Tarsounas M. Groelly FJ, et al. Among authors: blackford an. Nat Rev Cancer. 2023 Feb;23(2):78-94. doi: 10.1038/s41568-022-00535-5. Epub 2022 Dec 5. Nat Rev Cancer. 2023. PMID: 36471053 Review.
Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation.
Blackford AN, Patel RN, Forrester NA, Theil K, Groitl P, Stewart GS, Taylor AM, Morgan IM, Dobner T, Grand RJ, Turnell AS. Blackford AN, et al. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12251-6. doi: 10.1073/pnas.0914605107. Epub 2010 Jun 21. Proc Natl Acad Sci U S A. 2010. PMID: 20566845 Free PMC article.
BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks.
Higgs MR, Reynolds JJ, Winczura A, Blackford AN, Borel V, Miller ES, Zlatanou A, Nieminuszczy J, Ryan EL, Davies NJ, Stankovic T, Boulton SJ, Niedzwiedz W, Stewart GS. Higgs MR, et al. Among authors: blackford an. Mol Cell. 2015 Aug 6;59(3):462-77. doi: 10.1016/j.molcel.2015.06.007. Epub 2015 Jul 9. Mol Cell. 2015. PMID: 26166705 Free article.
35 results