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5-ht6 receptors as emerging targets for drug discovery.
Branchek TA, Blackburn TP. Branchek TA, et al. Among authors: blackburn tp. Annu Rev Pharmacol Toxicol. 2000;40:319-34. doi: 10.1146/annurev.pharmtox.40.1.319. Annu Rev Pharmacol Toxicol. 2000. PMID: 10836139 Review.
Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299.
Swanson CJ, Blackburn TP, Zhang X, Zheng K, Xu ZQ, Hökfelt T, Wolinsky TD, Konkel MJ, Chen H, Zhong H, Walker MW, Craig DA, Gerald CP, Branchek TA. Swanson CJ, et al. Among authors: blackburn tp. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. doi: 10.1073/pnas.0508970102. Epub 2005 Nov 15. Proc Natl Acad Sci U S A. 2005. PMID: 16287967 Free PMC article.
The medical benefit of 5-HT research.
Jones BJ, Blackburn TP. Jones BJ, et al. Among authors: blackburn tp. Pharmacol Biochem Behav. 2002 Apr;71(4):555-68. doi: 10.1016/s0091-3057(01)00745-6. Pharmacol Biochem Behav. 2002. PMID: 11888547 Review.
In memory of Norman Bowery (1944-2016).
Trist DG, Kenakin TP, Blackburn TP. Trist DG, et al. Among authors: blackburn tp. Curr Opin Pharmacol. 2017 Aug;35:89-93. doi: 10.1016/j.coph.2017.05.008. Epub 2017 Aug 29. Curr Opin Pharmacol. 2017. PMID: 28864032
3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists.
Konkel MJ, Lagu B, Boteju LW, Jimenez H, Noble S, Walker MW, Chandrasena G, Blackburn TP, Nikam SS, Wright JL, Kornberg BE, Gregory T, Pugsley TA, Akunne H, Zoski K, Wise LD. Konkel MJ, et al. Among authors: blackburn tp. J Med Chem. 2006 Jun 29;49(13):3757-8. doi: 10.1021/jm060001n. J Med Chem. 2006. PMID: 16789730
SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety.
Wood MD, Reavill C, Trail B, Wilson A, Stean T, Kennett GA, Lightowler S, Blackburn TP, Thomas D, Gager TL, Riley G, Holland V, Bromidge SM, Forbes IT, Middlemiss DN. Wood MD, et al. Among authors: blackburn tp. Neuropharmacology. 2001 Aug;41(2):186-99. doi: 10.1016/s0028-3908(01)00054-5. Neuropharmacology. 2001. PMID: 11489455
82 results