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BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Ozer HG, El-Gamal D, Powell B, Hing ZA, Blachly JS, Harrington B, Mitchell S, Grieselhuber NR, Williams K, Lai TH, Alinari L, Baiocchi RA, Brinton L, Baskin E, Cannon M, Beaver L, Goettl VM, Lucas DM, Woyach JA, Sampath D, Lehman AM, Yu L, Zhang J, Ma Y, Zhang Y, Spevak W, Shi S, Severson P, Shellooe R, Carias H, Tsang G, Dong K, Ewing T, Marimuthu A, Tantoy C, Walters J, Sanftner L, Rezaei H, Nespi M, Matusow B, Habets G, Ibrahim P, Zhang C, Mathé EA, Bollag G, Byrd JC, Lapalombella R. Ozer HG, et al. Among authors: blachly js. Cancer Discov. 2018 Apr;8(4):458-477. doi: 10.1158/2159-8290.CD-17-0902. Epub 2018 Jan 31. Cancer Discov. 2018. PMID: 29386193 Free PMC article.
PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
El-Gamal D, Williams K, LaFollette TD, Cannon M, Blachly JS, Zhong Y, Woyach JA, Williams E, Awan FT, Jones J, Andritsos L, Maddocks K, Wu CH, Chen CS, Lehman A, Zhang X, Lapalombella R, Byrd JC. El-Gamal D, et al. Among authors: blachly js. Blood. 2014 Aug 28;124(9):1481-91. doi: 10.1182/blood-2014-05-574830. Epub 2014 Jul 7. Blood. 2014. PMID: 25001469 Free PMC article.
PrEMeR-CG: inferring nucleotide level DNA methylation values from MethylCap-seq data.
Frankhouser DE, Murphy M, Blachly JS, Park J, Zoller MW, Ganbat JO, Curfman J, Byrd JC, Lin S, Marcucci G, Yan P, Bundschuh R. Frankhouser DE, et al. Among authors: blachly js. Bioinformatics. 2014 Dec 15;30(24):3567-74. doi: 10.1093/bioinformatics/btu583. Epub 2014 Aug 31. Bioinformatics. 2014. PMID: 25178460 Free PMC article.
Reduced dose pentostatin for initial management of hairy cell leukemia patients who have active infection or risk of hemorrhage is safe and effective.
Andritsos LA, Dunavin N, Lozanski G, Jones JA, Blachly JS, Lucas DM, Byrd JC, Kraut E, Grever MR. Andritsos LA, et al. Among authors: blachly js. Haematologica. 2015 Jan;100(1):e18-20. doi: 10.3324/haematol.2014.113290. Epub 2014 Oct 31. Haematologica. 2015. PMID: 25361945 Free PMC article. No abstract available.
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in chronic lymphocytic leukemia.
Blachly JS, Ruppert AS, Zhao W, Long S, Flynn J, Flinn I, Jones J, Maddocks K, Andritsos L, Ghia EM, Rassenti LZ, Kipps TJ, de la Chapelle A, Byrd JC. Blachly JS, et al. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4322-7. doi: 10.1073/pnas.1503587112. Epub 2015 Mar 18. Proc Natl Acad Sci U S A. 2015. PMID: 25787252 Free PMC article.
MuCor: mutation aggregation and correlation.
Kroll KW, Eisfeld AK, Lozanski G, Bloomfield CD, Byrd JC, Blachly JS. Kroll KW, et al. Among authors: blachly js. Bioinformatics. 2016 May 15;32(10):1557-8. doi: 10.1093/bioinformatics/btw028. Epub 2016 Jan 23. Bioinformatics. 2016. PMID: 26803155 Free PMC article.
107 results