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TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, Cropper H, Jain P, Liu Q, Mehta SS, Zuckerman AJ, Xin M, Umans J, Huang J, Durairaj AS, Serrano GE, Beach TG, Greicius MD, James ML, Buckwalter MS, McReynolds MR, Rabinowitz JD, Andreasson KI. Wilson EN, et al. Among authors: blacher e. Nat Neurosci. 2024 Mar 27. doi: 10.1038/s41593-024-01610-w. Online ahead of print. Nat Neurosci. 2024. PMID: 38539014
Aging disrupts circadian gene regulation and function in macrophages.
Blacher E, Tsai C, Litichevskiy L, Shipony Z, Iweka CA, Schneider KM, Chuluun B, Heller HC, Menon V, Thaiss CA, Andreasson KI. Blacher E, et al. Nat Immunol. 2022 Feb;23(2):229-236. doi: 10.1038/s41590-021-01083-0. Epub 2021 Dec 23. Nat Immunol. 2022. PMID: 34949832 Free PMC article.
Can microbes combat neurodegeneration?
Blacher E. Blacher E. Science. 2021 Jul 9;373(6551):172-173. doi: 10.1126/science.abi9353. Science. 2021. PMID: 34244406 No abstract available.
CD38 in cancer-associated fibroblasts promotes pro-tumoral activity.
Ben Baruch B, Mantsur E, Franco-Barraza J, Blacher E, Cukierman E, Stein R. Ben Baruch B, et al. Among authors: blacher e. Lab Invest. 2020 Dec;100(12):1517-1531. doi: 10.1038/s41374-020-0458-8. Epub 2020 Jul 1. Lab Invest. 2020. PMID: 32612286 Free PMC article.
Potential roles of gut microbiome and metabolites in modulating ALS in mice.
Blacher E, Bashiardes S, Shapiro H, Rothschild D, Mor U, Dori-Bachash M, Kleimeyer C, Moresi C, Harnik Y, Zur M, Zabari M, Brik RB, Kviatcovsky D, Zmora N, Cohen Y, Bar N, Levi I, Amar N, Mehlman T, Brandis A, Biton I, Kuperman Y, Tsoory M, Alfahel L, Harmelin A, Schwartz M, Israelson A, Arike L, Johansson MEV, Hansson GC, Gotkine M, Segal E, Elinav E. Blacher E, et al. Nature. 2019 Aug;572(7770):474-480. doi: 10.1038/s41586-019-1443-5. Epub 2019 Jul 22. Nature. 2019. PMID: 31330533
Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection.
Thaiss CA, Levy M, Grosheva I, Zheng D, Soffer E, Blacher E, Braverman S, Tengeler AC, Barak O, Elazar M, Ben-Zeev R, Lehavi-Regev D, Katz MN, Pevsner-Fischer M, Gertler A, Halpern Z, Harmelin A, Aamar S, Serradas P, Grosfeld A, Shapiro H, Geiger B, Elinav E. Thaiss CA, et al. Among authors: blacher e. Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Science. 2018. PMID: 29519916 Free article.
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