Bjørn-Yoshimoto WE - Search Results

1

Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads.

Ramiro IBL, Bjørn-Yoshimoto WE, Imperial JS, Gajewiak J, Salcedo PF, Watkins M, Taylor D, Resager W, Ueberheide B, Bräuner-Osborne H, Whitby FG, Hill CP, Martin LF, Patwardhan A, Concepcion GP, Olivera BM, Safavi-Hemami H. Ramiro IBL, et al. Among authors: bjorn yoshimoto we. Sci Adv. 2022 Mar 25;8(12):eabk1410. doi: 10.1126/sciadv.abk1410. Epub 2022 Mar 23. Sci Adv. 2022. PMID: 35319982 Free PMC article.

2

Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research.

Bjørn-Yoshimoto WE, Ramiro IBL, Yandell M, McIntosh JM, Olivera BM, Ellgaard L, Safavi-Hemami H. Bjørn-Yoshimoto WE, et al. Biomedicines. 2020 Jul 22;8(8):235. doi: 10.3390/biomedicines8080235. Biomedicines. 2020. PMID: 32708023 Free PMC article. Review.

3

Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins.

Koch TL, Ramiro IBL, Flórez Salcedo P, Engholm E, Jensen KJ, Chase K, Olivera BM, Bjørn-Yoshimoto WE, Safavi-Hemami H. Koch TL, et al. Among authors: bjorn yoshimoto we. Mol Biol Evol. 2022 Apr 10;39(4):msac075. doi: 10.1093/molbev/msac075. Mol Biol Evol. 2022. PMID: 35383850 Free PMC article.

4

Identification and Structure-Activity Relationship Study of Imidazo[1,2-a]pyridine-3-amines as First Selective Inhibitors of Excitatory Amino Acid Transporter Subtype 3 (EAAT3).

Wu P, Bjørn-Yoshimoto WE, Staudt M, Jensen AA, Bunch L. Wu P, et al. Among authors: bjorn yoshimoto we. ACS Chem Neurosci. 2019 Oct 16;10(10):4414-4429. doi: 10.1021/acschemneuro.9b00447. Epub 2019 Oct 1. ACS Chem Neurosci. 2019. PMID: 31573179

5

β-Sulfonamido Functionalized Aspartate Analogues as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype Selectivity Profiles Arising from Subtle Structural Differences.

Hansen JC, Bjørn-Yoshimoto WE, Bisballe N, Nielsen B, Jensen AA, Bunch L. Hansen JC, et al. Among authors: bjorn yoshimoto we. J Med Chem. 2016 Oct 13;59(19):8771-8786. doi: 10.1021/acs.jmedchem.6b01066. Epub 2016 Sep 16. J Med Chem. 2016. PMID: 27636002

6

Identification of a New Class of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors Followed by a Structure-Activity Relationship Study.

Hansen SW, Erichsen MN, Fu B, Bjørn-Yoshimoto WE, Abrahamsen B, Hansen JC, Jensen AA, Bunch L. Hansen SW, et al. J Med Chem. 2016 Oct 13;59(19):8757-8770. doi: 10.1021/acs.jmedchem.6b01058. Epub 2016 Sep 14. J Med Chem. 2016. PMID: 27626828

7

Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities.

Jensen AA, Fahlke C, Bjørn-Yoshimoto WE, Bunch L. Jensen AA, et al. Curr Opin Pharmacol. 2015 Feb;20:116-23. doi: 10.1016/j.coph.2014.10.008. Epub 2014 Nov 5. Curr Opin Pharmacol. 2015. PMID: 25466154 Review.

8

Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH-102.

Haym I, Huynh TH, Hansen SW, Pedersen MH, Ruiz JA, Erichsen MN, Gynther M, Bjørn-Yoshimoto WE, Abrahamsen B, Bastlund JF, Bundgaard C, Eriksen AL, Jensen AA, Bunch L. Haym I, et al. ChemMedChem. 2016 Feb 17;11(4):403-19. doi: 10.1002/cmdc.201500527. Epub 2016 Jan 21. ChemMedChem. 2016. PMID: 26797816 Free article.

9

New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.

Huynh TH, Erichsen MN, Tora AS, Goudet C, Sagot E, Assaf Z, Thomsen C, Brodbeck R, Stensbøl TB, Bjørn-Yoshimoto WE, Nielsen B, Pin JP, Gefflaut T, Bunch L. Huynh TH, et al. J Med Chem. 2016 Feb 11;59(3):914-24. doi: 10.1021/acs.jmedchem.5b01333. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26814576

10

5-HT_2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, Wacker D, Han GW, Cheng J, Katritch V, Jensen AA, Hanson MA, Zhao S, Gloriam DE, Roth BL, Stevens RC, Liu ZJ. Peng Y, et al. Among authors: bjorn yoshimoto we. Cell. 2018 Feb 8;172(4):719-730.e14. doi: 10.1016/j.cell.2018.01.001. Epub 2018 Feb 1. Cell. 2018. PMID: 29398112 Free PMC article.

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