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Intranasal HSP70 administration protects against dopaminergic denervation and modulates neuroinflammatory response in the 6-OHDA rat model.
Tiefensee Ribeiro C, Peixoto DO, Santos L, Saibro-Girardi C, Brum PO, Carazza-Kessler FG, Somensi N, Behrens LMP, Bittencourt RR, Soares LS, Silveira AK, de Oliveira J, Moreira JCF, Gasparotto J, Gelain DP. Tiefensee Ribeiro C, et al. Among authors: bittencourt rr. Brain Behav Immun Health. 2021 Mar 31;14:100253. doi: 10.1016/j.bbih.2021.100253. eCollection 2021 Jul. Brain Behav Immun Health. 2021. PMID: 34589762 Free PMC article.
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).
Peixoto DO, Bittencourt RR, Gasparotto J, Kessler FGC, Brum PO, Somensi N, Girardi CS, Dos Santos da Silva L, Outeiro TF, Moreira JCF, Gelain DP. Peixoto DO, et al. Among authors: bittencourt rr. J Neurochem. 2023 Sep 3. doi: 10.1111/jnc.15956. Online ahead of print. J Neurochem. 2023. PMID: 37661637
Transgenerational inheritance of methylmercury and vitamin A-induced toxicological effects in a Wistar rats environmental-based model.
Carazza-Kessler FG, Campos MS, Bittencourt RR, Rosa-Silva HTD, Brum PO, Silveira AK, Teixeira AA, Ribeiro CT, Peixoto DO, Santos L, Andrade G, Panzenhagen AC, Scheibel IM, Gelain DP, Fonseca Moreira JC. Carazza-Kessler FG, et al. Among authors: bittencourt rr. Chemosphere. 2024 Mar;351:141239. doi: 10.1016/j.chemosphere.2024.141239. Epub 2024 Jan 23. Chemosphere. 2024. PMID: 38272134