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Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor.
Sukla S, Biswas S, Birkmann A, Lischka P, Zimmermann H, Field HJ. Sukla S, et al. Among authors: biswas s. J Antimicrob Chemother. 2010 Jul;65(7):1347-52. doi: 10.1093/jac/dkq135. Epub 2010 May 7. J Antimicrob Chemother. 2010. PMID: 20453068 Free PMC article.
Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model.
Biswas S, Sukla S, Goldner T, Field HJ, Kropeit D, Paulsen D, Welbers A, Ruebsamen-Schaeff H, Zimmermann H, Birkmann A. Biswas S, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3843-52. doi: 10.1128/AAC.02641-14. Epub 2014 Apr 21. Antimicrob Agents Chemother. 2014. PMID: 24752278 Free PMC article.
4,026 results