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De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer.
Singh A, Ruiz C, Bhalla K, Haley JA, Li QK, Acquaah-Mensah G, Montal E, Sudini KR, Skoulidis F, Wistuba II, Papadimitrakopoulou V, Heymach JV, Boros LG, Gabrielson E, Carretero J, Wong KK, Haley JD, Biswal S, Girnun GD. Singh A, et al. Among authors: biswal s. FASEB J. 2018 Jun 15;32(12):fj201800204. doi: 10.1096/fj.201800204. Online ahead of print. FASEB J. 2018. PMID: 29906244 Free PMC article.
., Gabrielson, E., Carretero, J., Wong, K.-k., Haley, J. D., Biswal, S., Girnun, G. D. De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer....
., Gabrielson, E., Carretero, J., Wong, K.-k., Haley, J. D., Biswal, S., Girnun, G. D. De novo lipogenesis represents a therap …
Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.
Singh A, Happel C, Manna SK, Acquaah-Mensah G, Carrerero J, Kumar S, Nasipuri P, Krausz KW, Wakabayashi N, Dewi R, Boros LG, Gonzalez FJ, Gabrielson E, Wong KK, Girnun G, Biswal S. Singh A, et al. Among authors: biswal s. J Clin Invest. 2013 Jul;123(7):2921-34. doi: 10.1172/JCI66353. Epub 2013 Jun 10. J Clin Invest. 2013. PMID: 23921124 Free PMC article.
NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes.
Singh A, Daemen A, Nickles D, Jeon SM, Foreman O, Sudini K, Gnad F, Lajoie S, Gour N, Mitzner W, Chatterjee S, Choi EJ, Ravishankar B, Rappaport A, Patil N, McCleland M, Johnson L, Acquaah-Mensah G, Gabrielson E, Biswal S, Hatzivassiliou G. Singh A, et al. Among authors: biswal s. Clin Cancer Res. 2021 Feb 1;27(3):877-888. doi: 10.1158/1078-0432.CCR-20-1985. Epub 2020 Oct 19. Clin Cancer Res. 2021. PMID: 33077574 Free PMC article.
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
Singh A, Misra V, Thimmulappa RK, Lee H, Ames S, Hoque MO, Herman JG, Baylin SB, Sidransky D, Gabrielson E, Brock MV, Biswal S. Singh A, et al. Among authors: biswal s. PLoS Med. 2006 Oct;3(10):e420. doi: 10.1371/journal.pmed.0030420. PLoS Med. 2006. PMID: 17020408 Free PMC article.
Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors.
Singh A, Venkannagari S, Oh KH, Zhang YQ, Rohde JM, Liu L, Nimmagadda S, Sudini K, Brimacombe KR, Gajghate S, Ma J, Wang A, Xu X, Shahane SA, Xia M, Woo J, Mensah GA, Wang Z, Ferrer M, Gabrielson E, Li Z, Rastinejad F, Shen M, Boxer MB, Biswal S. Singh A, et al. Among authors: biswal s. ACS Chem Biol. 2016 Nov 18;11(11):3214-3225. doi: 10.1021/acschembio.6b00651. Epub 2016 Oct 17. ACS Chem Biol. 2016. PMID: 27552339 Free PMC article.
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.
Singh A, Boldin-Adamsky S, Thimmulappa RK, Rath SK, Ashush H, Coulter J, Blackford A, Goodman SN, Bunz F, Watson WH, Gabrielson E, Feinstein E, Biswal S. Singh A, et al. Among authors: biswal s. Cancer Res. 2008 Oct 1;68(19):7975-84. doi: 10.1158/0008-5472.CAN-08-1401. Cancer Res. 2008. PMID: 18829555 Free PMC article.
544 results