Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function.
Sussan TE, Gajghate S, Chatterjee S, Mandke P, McCormick S, Sudini K, Kumar S, Breysse PN, Diette GB, Sidhaye VK, Biswal S.
Sussan TE, et al. Among authors: biswal s.
Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L27-36. doi: 10.1152/ajplung.00398.2014. Epub 2015 May 8.
Am J Physiol Lung Cell Mol Physiol. 2015.
PMID: 25957295
Free PMC article.
We previously demonstrated that Nrf2-deficient mice have heightened susceptibility to asthma, including elevated oxidative stress, inflammation, mucus, and airway hyperresponsiveness (AHR) (Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, Yamamoto M, Kensler TW, Tuder …
We previously demonstrated that Nrf2-deficient mice have heightened susceptibility to asthma, including elevated oxidative stress, inflammat …