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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities.
Zhang Y, Remillard D, Onubogu U, Karakyriakou B, Asiaban JN, Ramos AR, Bowland K, Bishop TR, Barta PA, Nance S, Durbin AD, Ott CJ, Janiszewska M, Cravatt BF, Erb MA. Zhang Y, et al. Among authors: bishop tr. Nat Struct Mol Biol. 2023 Aug;30(8):1160-1171. doi: 10.1038/s41594-023-01041-4. Epub 2023 Jul 24. Nat Struct Mol Biol. 2023. PMID: 37488358 Free PMC article.
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia.
Garnar-Wortzel L, Bishop TR, Kitamura S, Milosevich N, Asiaban JN, Zhang X, Zheng Q, Chen E, Ramos AR, Ackerman CJ, Hampton EN, Chatterjee AK, Young TS, Hull MV, Sharpless KB, Cravatt BF, Wolan DW, Erb MA. Garnar-Wortzel L, et al. Among authors: bishop tr. ACS Cent Sci. 2021 May 26;7(5):815-830. doi: 10.1021/acscentsci.0c01550. Epub 2021 Apr 30. ACS Cent Sci. 2021. PMID: 34079898 Free PMC article.
Cell-Based Ligand Discovery for the ENL YEATS Domain.
Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA. Asiaban JN, et al. Among authors: bishop tr. ACS Chem Biol. 2020 Apr 17;15(4):895-903. doi: 10.1021/acschembio.0c00124. Epub 2020 Mar 19. ACS Chem Biol. 2020. PMID: 32176478 Free PMC article.
44 results