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An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.
Shulman DS, Whittle SB, Surdez D, Bailey KM, de Álava E, Yustein JT, Shlien A, Hayashi M, Bishop AJR, Crompton BD, DuBois SG, Shukla N, Leavey PJ, Lessnick SL, Kovar H, Delattre O, Grünewald TGP, Antonescu CR, Roberts RD, Toretsky JA, Tirode F, Gorlick R, Janeway KA, Reed D, Lawlor ER, Grohar PJ. Shulman DS, et al. Among authors: bishop ajr. NPJ Precis Oncol. 2022 Sep 17;6(1):65. doi: 10.1038/s41698-022-00307-2. NPJ Precis Oncol. 2022. PMID: 36115869 Free PMC article. Review.
EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.
Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR. Gorthi A, et al. Among authors: bishop ajr. Nature. 2018 Mar 15;555(7696):387-391. doi: 10.1038/nature25748. Epub 2018 Mar 7. Nature. 2018. PMID: 29513652 Free PMC article.
Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children's Oncology Group Phase 1 Consortium study (ADVL1411).
Schafer ES, Rau RE, Berg SL, Liu X, Minard CG, Bishop AJR, Romero JC, Hicks MJ, Nelson MD Jr, Voss S, Reid JM, Fox E, Weigel BJ, Blaney SM. Schafer ES, et al. Among authors: bishop ajr. Pediatr Blood Cancer. 2020 Feb;67(2):e28073. doi: 10.1002/pbc.28073. Epub 2019 Nov 14. Pediatr Blood Cancer. 2020. PMID: 31724813 Free PMC article. Clinical Trial.
RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma.
Randolph ME, Afifi M, Gorthi A, Weil R, Wilky BA, Weinreb J, Ciero P, Ter Hoeve N, van Diest PJ, Raman V, Bishop AJR, Loeb DM. Randolph ME, et al. Among authors: bishop ajr. bioRxiv [Preprint]. 2023 Jun 10:2023.06.10.544474. doi: 10.1101/2023.06.10.544474. bioRxiv. 2023. PMID: 37333164 Free PMC article. Updated. Preprint.
RNA helicase DDX3 regulates RAD51 localization and DNA damage repair in Ewing sarcoma.
Randolph ME, Afifi M, Gorthi A, Weil R, Wilky BA, Weinreb J, Ciero P, Hoeve NT, van Diest PJ, Raman V, Bishop AJR, Loeb DM. Randolph ME, et al. Among authors: bishop ajr. iScience. 2024 Jan 16;27(2):108925. doi: 10.1016/j.isci.2024.108925. eCollection 2024 Feb 16. iScience. 2024. PMID: 38323009 Free PMC article.
The molecular landscape of ETMR at diagnosis and relapse.
Lambo S, Gröbner SN, Rausch T, Waszak SM, Schmidt C, Gorthi A, Romero JC, Mauermann M, Brabetz S, Krausert S, Buchhalter I, Koster J, Zwijnenburg DA, Sill M, Hübner JM, Mack N, Schwalm B, Ryzhova M, Hovestadt V, Papillon-Cavanagh S, Chan JA, Landgraf P, Ho B, Milde T, Witt O, Ecker J, Sahm F, Sumerauer D, Ellison DW, Orr BA, Darabi A, Haberler C, Figarella-Branger D, Wesseling P, Schittenhelm J, Remke M, Taylor MD, Gil-da-Costa MJ, Łastowska M, Grajkowska W, Hasselblatt M, Hauser P, Pietsch T, Uro-Coste E, Bourdeaut F, Masliah-Planchon J, Rigau V, Alexandrescu S, Wolf S, Li XN, Schüller U, Snuderl M, Karajannis MA, Giangaspero F, Jabado N, von Deimling A, Jones DTW, Korbel JO, von Hoff K, Lichter P, Huang A, Bishop AJR, Pfister SM, Korshunov A, Kool M. Lambo S, et al. Among authors: bishop ajr. Nature. 2019 Dec;576(7786):274-280. doi: 10.1038/s41586-019-1815-x. Epub 2019 Dec 4. Nature. 2019. PMID: 31802000 Free PMC article.
66 results