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HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity.
Leus NG, van der Wouden PE, van den Bosch T, Hooghiemstra WTR, Ourailidou ME, Kistemaker LE, Bischoff R, Gosens R, Haisma HJ, Dekker FJ. Leus NG, et al. Among authors: bischoff r. Biochem Pharmacol. 2016 May 15;108:58-74. doi: 10.1016/j.bcp.2016.03.010. Epub 2016 Mar 16. Biochem Pharmacol. 2016. PMID: 26993378 Free PMC article.
Antibody-free detection of protein tyrosine nitration in tissue sections.
Wisastra R, Poelstra K, Bischoff R, Maarsingh H, Haisma HJ, Dekker FJ. Wisastra R, et al. Among authors: bischoff r. Chembiochem. 2011 Sep 5;12(13):2016-20. doi: 10.1002/cbic.201100148. Epub 2011 Jul 11. Chembiochem. 2011. PMID: 21748837 No abstract available.
Enrichment and detection of tyrosine-nitrated proteins.
Dekker F, Abello N, Wisastra R, Bischoff R. Dekker F, et al. Among authors: bischoff r. Curr Protoc Protein Sci. 2012 Aug;Chapter 14:14.13.1-14.13.19. doi: 10.1002/0471140864.ps1413s69. Curr Protoc Protein Sci. 2012. PMID: 22851496
A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [¹⁸F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging.
Matusiak N, Castelli R, Tuin AW, Overkleeft HS, Wisastra R, Dekker FJ, Prély LM, Bischoff R, van Waarde A, Dierckx RA, Elsinga PH. Matusiak N, et al. Among authors: bischoff r. Bioorg Med Chem. 2015 Jan 1;23(1):192-202. doi: 10.1016/j.bmc.2014.11.013. Epub 2014 Nov 15. Bioorg Med Chem. 2015. PMID: 25438884
A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices.
van den Bosch T, Leus NGJ, Wapenaar H, Boichenko A, Hermans J, Bischoff R, Haisma HJ, Dekker FJ. van den Bosch T, et al. Among authors: bischoff r. Pulm Pharmacol Ther. 2017 Jun;44:88-95. doi: 10.1016/j.pupt.2017.03.006. Epub 2017 Mar 16. Pulm Pharmacol Ther. 2017. PMID: 28323055 Free PMC article.
HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice.
Leus NG, van den Bosch T, van der Wouden PE, Krist K, Ourailidou ME, Eleftheriadis N, Kistemaker LE, Bos S, Gjaltema RA, Mekonnen SA, Bischoff R, Gosens R, Haisma HJ, Dekker FJ. Leus NG, et al. Among authors: bischoff r. Sci Rep. 2017 Mar 27;7:45047. doi: 10.1038/srep45047. Sci Rep. 2017. PMID: 28344354 Free PMC article.
382 results