Birzin ET - Search Results

1

Antidiabetic activity of a highly potent and selective nonpeptide somatostatin receptor subtype-2 agonist.

Strowski MZ, Cashen DE, Birzin ET, Yang L, Singh V, Jacks TM, Nowak KW, Rohrer SP, Patchett AA, Smith RG, Schaeffer JM. Strowski MZ, et al. Among authors: birzin et. Endocrinology. 2006 Oct;147(10):4664-73. doi: 10.1210/en.2006-0274. Epub 2006 Jul 20. Endocrinology. 2006. PMID: 16857751

2

Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.

Yang L, Berk SC, Rohrer SP, Mosley RT, Guo L, Underwood DJ, Arison BH, Birzin ET, Hayes EC, Mitra SW, Parmar RM, Cheng K, Wu TJ, Butler BS, Foor F, Pasternak A, Pan Y, Silva M, Freidinger RM, Smith RG, Chapman K, Schaeffer JM, Patchett AA. Yang L, et al. Among authors: birzin et. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10836-41. doi: 10.1073/pnas.95.18.10836. Proc Natl Acad Sci U S A. 1998. PMID: 9724791 Free PMC article.

3

Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.

Rohrer SP, Birzin ET, Mosley RT, Berk SC, Hutchins SM, Shen DM, Xiong Y, Hayes EC, Parmar RM, Foor F, Mitra SW, Degrado SJ, Shu M, Klopp JM, Cai SJ, Blake A, Chan WW, Pasternak A, Yang L, Patchett AA, Smith RG, Chapman KT, Schaeffer JM. Rohrer SP, et al. Among authors: birzin et. Science. 1998 Oct 23;282(5389):737-40. doi: 10.1126/science.282.5389.737. Science. 1998. PMID: 9784130

4

Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists.

Zhou C, Guo L, Morriello G, Pasternak A, Pan Y, Rohrer SP, Birzin ET, Huskey SE, Jacks T, Schleim KD, Cheng K, Schaeffer JM, Patchett AA, Yang L. Zhou C, et al. Among authors: birzin et. Bioorg Med Chem Lett. 2001 Feb 12;11(3):415-7. doi: 10.1016/s0960-894x(00)00687-9. Bioorg Med Chem Lett. 2001. PMID: 11212124

5

Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists.

Yang L, Guo L, Pasternak A, Mosley R, Rohrer S, Birzin E, Foor F, Cheng K, Schaeffer J, Patchett AA. Yang L, et al. J Med Chem. 1998 Jun 18;41(13):2175-9. doi: 10.1021/jm980194h. J Med Chem. 1998. PMID: 9632348 No abstract available.

6

Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization.

Pasternak A, Pan Y, Marino D, Sanderson PE, Mosley R, Rohrer SP, Birzin ET, Huskey SE, Jacks T, Schleim KD, Cheng K, Schaeffer JM, Patchett AA, Yang L. Pasternak A, et al. Among authors: birzin et. Bioorg Med Chem Lett. 1999 Feb 8;9(3):491-6. doi: 10.1016/s0960-894x(99)00016-5. Bioorg Med Chem Lett. 1999. PMID: 10091708

7

A combinatorial approach toward the discovery of non-peptide, subtype-selective somatostatin receptor ligands.

Berk SC, Rohrer SP, Degrado SJ, Birzin ET, Mosley RT, Hutchins SM, Pasternak A, Schaeffer JM, Underwood DJ, Chapman KT. Berk SC, et al. Among authors: birzin et. J Comb Chem. 1999 Sep-Oct;1(5):388-96. doi: 10.1021/cc990017h. J Comb Chem. 1999. PMID: 10748735

8

High-throughput receptor-binding methods for somatostatin receptor 2.

Birzin ET, Rohrer SP. Birzin ET, et al. Anal Biochem. 2002 Aug 1;307(1):159-66. doi: 10.1016/s0003-2697(02)00007-6. Anal Biochem. 2002. PMID: 12137793

9

Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha.

Dykstra KD, Guo L, Birzin ET, Chan W, Yang YT, Hayes EC, DaSilva CA, Pai LY, Mosley RT, Kraker B, Fitzgerald PM, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Dykstra KD, et al. Among authors: birzin et. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2322-8. doi: 10.1016/j.bmcl.2007.01.054. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17289385

10

Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity.

Chen HY, Dykstra KD, Birzin ET, Frisch K, Chan W, Yang YT, Mosley RT, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Chen HY, et al. Among authors: birzin et. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1417-21. doi: 10.1016/j.bmcl.2004.01.031. Bioorg Med Chem Lett. 2004. PMID: 15006374

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