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Page 1
Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents.
Torres E, Moreno-Viguri E, Galiano S, Devarapally G, Crawford PW, Azqueta A, Arbillaga L, Varela J, Birriel E, Di Maio R, Cerecetto H, González M, Aldana I, Monge A, Pérez-Silanes S. Torres E, et al. Among authors: birriel e. Eur J Med Chem. 2013 Aug;66:324-34. doi: 10.1016/j.ejmech.2013.04.065. Epub 2013 May 30. Eur J Med Chem. 2013. PMID: 23811257 Free article.
Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo.
Álvarez G, Martínez J, Varela J, Birriel E, Cruces E, Gabay M, Leal SM, Escobar P, Aguirre-López B, Cabrera N, Tuena de Gómez-Puyou M, Gómez Puyou A, Pérez-Montfort R, Yaluff G, Torres S, Serna E, Vera de Bilbao N, González M, Cerecetto H. Álvarez G, et al. Among authors: birriel e. Eur J Med Chem. 2015 Jul 15;100:246-56. doi: 10.1016/j.ejmech.2015.06.018. Epub 2015 Jun 12. Eur J Med Chem. 2015. PMID: 26094151
Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.
Aguilera E, Varela J, Birriel E, Serna E, Torres S, Yaluff G, de Bilbao NV, Aguirre-López B, Cabrera N, Díaz Mazariegos S, de Gómez-Puyou MT, Gómez-Puyou A, Pérez-Montfort R, Minini L, Merlino A, Cerecetto H, González M, Alvarez G. Aguilera E, et al. Among authors: birriel e. ChemMedChem. 2016 Jun 20;11(12):1328-38. doi: 10.1002/cmdc.201500385. Epub 2015 Oct 23. ChemMedChem. 2016. PMID: 26492824
Expanding the family of heteroleptic oxidovanadium(IV) compounds with salicylaldehyde semicarbazones and polypyridyl ligands showing anti-Trypanosoma cruzi activity.
Scalese G, Benítez J, Rostán S, Correia I, Bradford L, Vieites M, Minini L, Merlino A, Coitiño EL, Birriel E, Varela J, Cerecetto H, González M, Pessoa JC, Gambino D. Scalese G, et al. Among authors: birriel e. J Inorg Biochem. 2015 Jun;147:116-25. doi: 10.1016/j.jinorgbio.2015.03.002. Epub 2015 Mar 12. J Inorg Biochem. 2015. PMID: 25824466
Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans.
Soares FGN, Göethel G, Kagami LP, das Neves GM, Sauer E, Birriel E, Varela J, Gonçalves IL, Von Poser G, González M, Kawano DF, Paula FR, de Melo EB, Garcia SC, Cerecetto H, Eifler-Lima VL. Soares FGN, et al. Among authors: birriel e. BMC Pharmacol Toxicol. 2019 Dec 19;20(Suppl 1):76. doi: 10.1186/s40360-019-0357-z. BMC Pharmacol Toxicol. 2019. PMID: 31852548 Free PMC article.