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Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids.
Kolitz S, Hasson T, Towfic F, Funt JM, Bakshi S, Fowler KD, Laifenfeld D, Grinspan A, Artyomov MN, Birnberg T, Schwartz R, Komlosh A, Hayardeny L, Ladkani D, Hayden MR, Zeskind B, Grossman I. Kolitz S, et al. Among authors: birnberg t. Sci Rep. 2015 May 22;5:10191. doi: 10.1038/srep10191. Sci Rep. 2015. PMID: 25998228 Free PMC article.
Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition.
Hasson T, Kolitz S, Towfic F, Laifenfeld D, Bakshi S, Beriozkin O, Shacham-Abramson M, Timan B, Fowler KD, Birnberg T, Konya A, Komlosh A, Ladkani D, Hayden MR, Zeskind B, Grossman I. Hasson T, et al. Among authors: birnberg t. J Neuroimmunol. 2016 Jan 15;290:84-95. doi: 10.1016/j.jneuroim.2015.11.020. Epub 2015 Nov 24. J Neuroimmunol. 2016. PMID: 26711576 Free article.
Pridopidine activates neuroprotective pathways impaired in Huntington Disease.
Geva M, Kusko R, Soares H, Fowler KD, Birnberg T, Barash S, -Wagner AM, Fine T, Lysaght A, Weiner B, Cha Y, Kolitz S, Towfic F, Orbach A, Laufer R, Zeskind B, Grossman I, Hayden MR. Geva M, et al. Among authors: birnberg t. Hum Mol Genet. 2016 Sep 15;25(18):3975-3987. doi: 10.1093/hmg/ddw238. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466197 Free PMC article.
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor.
Kaye J, Piryatinsky V, Birnberg T, Hingaly T, Raymond E, Kashi R, Amit-Romach E, Caballero IS, Towfic F, Ator MA, Rubinstein E, Laifenfeld D, Orbach A, Shinar D, Marantz Y, Grossman I, Knappertz V, Hayden MR, Laufer R. Kaye J, et al. Among authors: birnberg t. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6145-E6152. doi: 10.1073/pnas.1607843113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671624 Free PMC article.
Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome.
Birnberg T, Bar-On L, Sapoznikov A, Caton ML, Cervantes-Barragán L, Makia D, Krauthgamer R, Brenner O, Ludewig B, Brockschnieder D, Riethmacher D, Reizis B, Jung S. Birnberg T, et al. Immunity. 2008 Dec 19;29(6):986-97. doi: 10.1016/j.immuni.2008.10.012. Epub 2008 Dec 8. Immunity. 2008. PMID: 19062318 Free article.
Uterine DCs are crucial for decidua formation during embryo implantation in mice.
Plaks V, Birnberg T, Berkutzki T, Sela S, BenYashar A, Kalchenko V, Mor G, Keshet E, Dekel N, Neeman M, Jung S. Plaks V, et al. Among authors: birnberg t. J Clin Invest. 2008 Dec;118(12):3954-65. doi: 10.1172/JCI36682. Epub 2008 Nov 20. J Clin Invest. 2008. PMID: 19033665 Free PMC article.
Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells.
Yogev N, Frommer F, Lukas D, Kautz-Neu K, Karram K, Ielo D, von Stebut E, Probst HC, van den Broek M, Riethmacher D, Birnberg T, Blank T, Reizis B, Korn T, Wiendl H, Jung S, Prinz M, Kurschus FC, Waisman A. Yogev N, et al. Among authors: birnberg t. Immunity. 2012 Aug 24;37(2):264-75. doi: 10.1016/j.immuni.2012.05.025. Epub 2012 Aug 16. Immunity. 2012. PMID: 22902234 Free article.