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Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation.
Song R, McAlpine W, Fond AM, Nair-Gill E, Choi JH, Nyström EEL, Arike L, Field S, Li X, SoRelle JA, Moresco JJ, Moresco EMY, Yates JR 3rd, Azadi P, Ni J, Birchenough GMH, Beutler B, Turer EE. Song R, et al. Among authors: birchenough gmh. Nat Commun. 2023 Jun 20;14(1):3652. doi: 10.1038/s41467-023-39398-1. Nat Commun. 2023. PMID: 37339972 Free PMC article.
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.
Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE, Wising C, Johansson ME, Hansson GC. Pelaseyed T, et al. Immunol Rev. 2014 Jul;260(1):8-20. doi: 10.1111/imr.12182. Immunol Rev. 2014. PMID: 24942678 Free PMC article. Review.
New developments in goblet cell mucus secretion and function.
Birchenough GM, Johansson ME, Gustafsson JK, Bergström JH, Hansson GC. Birchenough GM, et al. Mucosal Immunol. 2015 Jul;8(4):712-9. doi: 10.1038/mi.2015.32. Epub 2015 Apr 15. Mucosal Immunol. 2015. PMID: 25872481 Free PMC article. Review.
The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.
Erickson NA, Nyström EE, Mundhenk L, Arike L, Glauben R, Heimesaat MM, Fischer A, Bereswill S, Birchenough GM, Gruber AD, Johansson ME. Erickson NA, et al. PLoS One. 2015 Jul 10;10(7):e0131991. doi: 10.1371/journal.pone.0131991. eCollection 2015. PLoS One. 2015. PMID: 26162072 Free PMC article.
30 results