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PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model.
Katsouri L, Lim YM, Blondrath K, Eleftheriadou I, Lombardero L, Birch AM, Mirzaei N, Irvine EE, Mazarakis ND, Sastre M. Katsouri L, et al. Among authors: birch am. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12292-12297. doi: 10.1073/pnas.1606171113. Epub 2016 Oct 10. Proc Natl Acad Sci U S A. 2016. PMID: 27791018 Free PMC article.
Imidazoline ligand BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease.
Mirzaei N, Mota BC, Birch AM, Davis N, Romero-Molina C, Katsouri L, Palmer EOC, Golbano A, Riggall LJ, Nagy I, Tyacke R, Nutt DJ, Sastre M. Mirzaei N, et al. Among authors: birch am. Br J Pharmacol. 2021 Feb;178(3):654-671. doi: 10.1111/bph.15312. Epub 2020 Dec 27. Br J Pharmacol. 2021. PMID: 33140839 Free article.
29 results