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The role of LRRK2 in cytoskeletal dynamics.
Civiero L, Cogo S, Biosa A, Greggio E. Civiero L, et al. Among authors: biosa a. Biochem Soc Trans. 2018 Dec 17;46(6):1653-1663. doi: 10.1042/BST20180469. Epub 2018 Nov 22. Biochem Soc Trans. 2018. PMID: 30467120 Review.
Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.
Russo I, Kaganovich A, Ding J, Landeck N, Mamais A, Varanita T, Biosa A, Tessari I, Bubacco L, Greggio E, Cookson MR. Russo I, et al. Among authors: biosa a. Neurobiol Dis. 2019 Sep;129:67-78. doi: 10.1016/j.nbd.2019.05.012. Epub 2019 May 15. Neurobiol Dis. 2019. PMID: 31102768 Free PMC article.
Role of LRRK2 in the regulation of dopamine receptor trafficking.
Rassu M, Del Giudice MG, Sanna S, Taymans JM, Morari M, Brugnoli A, Frassineti M, Masala A, Esposito S, Galioto M, Valle C, Carri MT, Biosa A, Greggio E, Crosio C, Iaccarino C. Rassu M, et al. Among authors: biosa a. PLoS One. 2017 Jun 5;12(6):e0179082. doi: 10.1371/journal.pone.0179082. eCollection 2017. PLoS One. 2017. PMID: 28582422 Free PMC article.
Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype.
Rassu M, Biosa A, Galioto M, Fais M, Sini P, Greggio E, Piccoli G, Crosio C, Iaccarino C. Rassu M, et al. Among authors: biosa a. J Cell Mol Med. 2019 Dec;23(12):8505-8510. doi: 10.1111/jcmm.14674. Epub 2019 Sep 27. J Cell Mol Med. 2019. PMID: 31560168 Free PMC article.
LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation.
Pischedda F, Cirnaru MD, Ponzoni L, Sandre M, Biosa A, Carrion MP, Marin O, Morari M, Pan L, Greggio E, Bandopadhyay R, Sala M, Piccoli G. Pischedda F, et al. Among authors: biosa a. Brain. 2021 Jun 22;144(5):1509-1525. doi: 10.1093/brain/awab073. Brain. 2021. PMID: 33876242
The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1.
Perez Carrion M, Pischedda F, Biosa A, Russo I, Straniero L, Civiero L, Guida M, Gloeckner CJ, Ticozzi N, Tiloca C, Mariani C, Pezzoli G, Duga S, Pichler I, Pan L, Landers JE, Greggio E, Hess MW, Goldwurm S, Piccoli G. Perez Carrion M, et al. Among authors: biosa a. Front Mol Neurosci. 2018 Feb 28;11:64. doi: 10.3389/fnmol.2018.00064. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29541021 Free PMC article.
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