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Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.
Dekker J, Alber F, Aufmkolk S, Beliveau BJ, Bruneau BG, Belmont AS, Bintu L, Boettiger A, Calandrelli R, Disteche CM, Gilbert DM, Gregor T, Hansen AS, Huang B, Huangfu D, Kalhor R, Leslie CS, Li W, Li Y, Ma J, Noble WS, Park PJ, Phillips-Cremins JE, Pollard KS, Rafelski SM, Ren B, Ruan Y, Shav-Tal Y, Shen Y, Shendure J, Shu X, Strambio-De-Castillia C, Vertii A, Zhang H, Zhong S. Dekker J, et al. Among authors: bintu l. Mol Cell. 2023 Aug 3;83(15):2624-2640. doi: 10.1016/j.molcel.2023.06.018. Epub 2023 Jul 6. Mol Cell. 2023. PMID: 37419111 Review.
Dynamics of epigenetic regulation at the single-cell level.
Bintu L, Yong J, Antebi YE, McCue K, Kazuki Y, Uno N, Oshimura M, Elowitz MB. Bintu L, et al. Science. 2016 Feb 12;351(6274):720-4. doi: 10.1126/science.aab2956. Science. 2016. PMID: 26912859 Free PMC article.
The sound of silence: Transgene silencing in mammalian cell engineering.
Cabrera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, Khalil AS, Wong WW, Collins JJ, Rosser SJ, Polizzi K, Elowitz MB, Fussenegger M, Hilton IB, Leonard JN, Bintu L, Galloway KE, Deans TL. Cabrera A, et al. Among authors: bintu l. Cell Syst. 2022 Dec 21;13(12):950-973. doi: 10.1016/j.cels.2022.11.005. Cell Syst. 2022. PMID: 36549273 Free PMC article. Review.
Large-scale mapping and mutagenesis of human transcriptional effector domains.
DelRosso N, Tycko J, Suzuki P, Andrews C, Aradhana, Mukund A, Liongson I, Ludwig C, Spees K, Fordyce P, Bassik MC, Bintu L. DelRosso N, et al. Among authors: bintu l. Nature. 2023 Apr;616(7956):365-372. doi: 10.1038/s41586-023-05906-y. Epub 2023 Apr 5. Nature. 2023. PMID: 37020022 Free PMC article.
High-Throughput Discovery and Characterization of Human Transcriptional Effectors.
Tycko J, DelRosso N, Hess GT, Aradhana, Banerjee A, Mukund A, Van MV, Ego BK, Yao D, Spees K, Suzuki P, Marinov GK, Kundaje A, Bassik MC, Bintu L. Tycko J, et al. Among authors: bintu l. Cell. 2020 Dec 23;183(7):2020-2035.e16. doi: 10.1016/j.cell.2020.11.024. Epub 2020 Dec 15. Cell. 2020. PMID: 33326746 Free PMC article.
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.
Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, Phanstiel DH, Snyder MP, Bintu L, Greenleaf WJ, Kundaje A, Bassik MC. Tycko J, et al. Among authors: bintu l. Nat Commun. 2019 Sep 6;10(1):4063. doi: 10.1038/s41467-019-11955-7. Nat Commun. 2019. PMID: 31492858 Free PMC article.
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