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Hsp90 and FKBP51: complex regulators of psychiatric diseases.
Criado-Marrero M, Rein T, Binder EB, Porter JT, Koren J 3rd, Blair LJ. Criado-Marrero M, et al. Among authors: binder eb. Philos Trans R Soc Lond B Biol Sci. 2018 Jan 19;373(1738):20160532. doi: 10.1098/rstb.2016.0532. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29203717 Free PMC article. Review.
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Köhnlein O, Dabitz H, Brückl T, Müller N, Pfister H, Lieb R, Mueller JC, Lõhmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Muller-Myhsok B. Binder EB, et al. Nat Genet. 2004 Dec;36(12):1319-25. doi: 10.1038/ng1479. Epub 2004 Nov 21. Nat Genet. 2004. PMID: 15565110
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.
Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, Binder EB. Klengel T, et al. Among authors: binder eb. Nat Neurosci. 2013 Jan;16(1):33-41. doi: 10.1038/nn.3275. Epub 2012 Dec 2. Nat Neurosci. 2013. PMID: 23201972 Free PMC article.
FKBP5 and attention bias for threat: associations with hippocampal function and shape.
Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J, Glover E, Jovanovic T, Bradley B, Dinov ID, Zamanyan A, Toga AW, Binder EB, Ressler KJ. Fani N, et al. Among authors: binder eb. JAMA Psychiatry. 2013 Apr;70(4):392-400. doi: 10.1001/2013.jamapsychiatry.210. JAMA Psychiatry. 2013. PMID: 23407841 Free PMC article.
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC 3rd, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, Binder EB, Kayed R, Golde TE, Berchtold N, Dickey CA. Blair LJ, et al. Among authors: binder eb. J Clin Invest. 2013 Oct;123(10):4158-69. doi: 10.1172/JCI69003. Epub 2013 Sep 3. J Clin Invest. 2013. PMID: 23999428 Free PMC article.
FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications.
Gassen NC, Hartmann J, Zannas AS, Kretzschmar A, Zschocke J, Maccarrone G, Hafner K, Zellner A, Kollmannsberger LK, Wagner KV, Mehta D, Kloiber S, Turck CW, Lucae S, Chrousos GP, Holsboer F, Binder EB, Ising M, Schmidt MV, Rein T. Gassen NC, et al. Among authors: binder eb. Mol Psychiatry. 2016 Feb;21(2):277-89. doi: 10.1038/mp.2015.38. Epub 2015 Apr 7. Mol Psychiatry. 2016. PMID: 25849320
394 results