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Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.
Kiss MG, Papac-Miličević N, Porsch F, Tsiantoulas D, Hendrikx T, Takaoka M, Dinh HQ, Narzt MS, Göderle L, Ozsvár-Kozma M, Schuster M, Fortelny N, Hladik A, Knapp S, Gruber F, Pickering MC, Bock C, Swirski FK, Ley K, Zernecke A, Cochain C, Kemper C, Mallat Z, Binder CJ. Kiss MG, et al. Among authors: binder cj. Immunity. 2023 Aug 8;56(8):1809-1824.e10. doi: 10.1016/j.immuni.2023.06.026. Epub 2023 Jul 26. Immunity. 2023. PMID: 37499656
Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis.
van Os BW, Kusters PJH, den Toom M, Beckers L, van Tiel CM, Vos WG, de Jong E, Kieser A, van Roomen C, Binder CJ, Reiche ME, de Winther MP, Bosmans LA, Lutgens E. van Os BW, et al. Among authors: binder cj. Front Cardiovasc Med. 2023 May 5;10:1171764. doi: 10.3389/fcvm.2023.1171764. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37215541 Free PMC article.
Loss of TET2 increases B-1 cell number and IgM production while limiting CDR3 diversity.
Dennis E, Murach M, Blackburn CMR, Marshall M, Root K, Pattarabanjird T, Deroissart J, Erickson LD, Binder CJ, Bekiranov S, McNamara CA. Dennis E, et al. Among authors: binder cj. Front Immunol. 2024 Mar 27;15:1380641. doi: 10.3389/fimmu.2024.1380641. eCollection 2024. Front Immunol. 2024. PMID: 38601144 Free PMC article.
Marginal zone B cells produce 'natural' atheroprotective IgM antibodies in a T cell-dependent manner.
Harrison J, Newland SA, Jiang W, Giakomidi D, Zhao X, Clement M, Masters L, Corovic A, Zhang X, Drago F, Ma M, Ozsvar Kozma M, Yasin F, Saady Y, Kothari H, Zhao TX, Shi GP, McNamara CA, Binder CJ, Sage AP, Tarkin JM, Mallat Z, Nus M. Harrison J, et al. Among authors: binder cj. Cardiovasc Res. 2024 Mar 14;120(3):318-328. doi: 10.1093/cvr/cvae027. Cardiovasc Res. 2024. PMID: 38381113 Free PMC article.
Single-cell profiling reveals age-associated immunity in atherosclerosis.
Smit V, de Mol J, Schaftenaar FH, Depuydt MAC, Postel RJ, Smeets D, Verheijen FWM, Bogers L, van Duijn J, Verwilligen RAF, Grievink HW, Bernabé Kleijn MNA, van Ingen E, de Jong MJM, Goncalves L, Peeters JAHM, Smeets HJ, Wezel A, Polansky JK, de Winther MPJ, Binder CJ, Tsiantoulas D, Bot I, Kuiper J, Foks AC. Smit V, et al. Among authors: binder cj. Cardiovasc Res. 2023 Nov 25;119(15):2508-2521. doi: 10.1093/cvr/cvad099. Cardiovasc Res. 2023. PMID: 37390467 Free PMC article.
212 results