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Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH.
Hendrikx T, Porsch F, Kiss MG, Rajcic D, Papac-Miličević N, Hoebinger C, Goederle L, Hladik A, Shaw LE, Horstmann H, Knapp S, Derdak S, Bilban M, Heintz L, Krawczyk M, Paternostro R, Trauner M, Farlik M, Wolf D, Binder CJ. Hendrikx T, et al. Among authors: binder cj. J Hepatol. 2022 Nov;77(5):1373-1385. doi: 10.1016/j.jhep.2022.06.004. Epub 2022 Jun 21. J Hepatol. 2022. PMID: 35750138 Free article.
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.
Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lütjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. Bieghs V, et al. Among authors: binder cj. PLoS One. 2012;7(1):e30668. doi: 10.1371/journal.pone.0030668. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295101 Free PMC article.
CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies.
Wolf D, Jehle F, Ortiz Rodriguez A, Dufner B, Hoppe N, Colberg C, Lozhkin A, Bassler N, Rupprecht B, Wiedemann A, Hilgendorf I, Stachon P, Willecke F, Febbraio M, von zur Muhlen C, Binder CJ, Bode C, Zirlik A, Peter K. Wolf D, et al. Among authors: binder cj. PLoS One. 2012;7(3):e33026. doi: 10.1371/journal.pone.0033026. Epub 2012 Mar 8. PLoS One. 2012. PMID: 22412980 Free PMC article.
WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs.
Matt U, Sharif O, Martins R, Furtner T, Langeberg L, Gawish R, Elbau I, Zivkovic A, Lakovits K, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder CJ, Bochkov VN, Scott JD, Knapp S. Matt U, et al. Among authors: binder cj. J Clin Invest. 2013 Jul;123(7):3014-24. doi: 10.1172/JCI60681. Epub 2013 Jun 24. J Clin Invest. 2013. PMID: 23934128 Free PMC article.
Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
Hendrikx T, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Jeurissen ML, Steinbusch MM, Vaes N, Binder CJ, Koek GH, Stienstra R, Netea MG, Hofker MH, Shiri-Sverdlov R. Hendrikx T, et al. Among authors: binder cj. PLoS One. 2013 Dec 2;8(12):e78792. doi: 10.1371/journal.pone.0078792. eCollection 2013. PLoS One. 2013. PMID: 24312444 Free PMC article.
219 results