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Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM, Pryor M, Yang ZH, Remaley AT, Mollnes TE, Hewitt SM, Yan B, Kazemian M, Kiss MG, Binder CJ, Halvorsen B, Espevik T, Kemper C. Niyonzima N, et al. Among authors: binder cj. Sci Immunol. 2021 Dec 24;6(66):eabf2489. doi: 10.1126/sciimmunol.abf2489. Epub 2021 Dec 24. Sci Immunol. 2021. PMID: 34932384 Free PMC article.
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.
Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt M, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. Salzer E, et al. Among authors: binder cj. Sci Immunol. 2020 Jul 10;5(49):eabc3979. doi: 10.1126/sciimmunol.abc3979. Sci Immunol. 2020. PMID: 32646852 Free PMC article.
The multifaceted impact of complement on atherosclerosis.
Kiss MG, Binder CJ. Kiss MG, et al. Among authors: binder cj. Atherosclerosis. 2022 Jun;351:29-40. doi: 10.1016/j.atherosclerosis.2022.03.014. Epub 2022 Mar 17. Atherosclerosis. 2022. PMID: 35365353 Free article. Review.
Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis.
Douna H, Smit V, van Puijvelde GHM, Kiss MG, Binder CJ, Bot L, Kuchroo VK, Lichtman AH, Kuiper J, Foks AC. Douna H, et al. Among authors: binder cj. Atherosclerosis. 2022 Jul;352:1-9. doi: 10.1016/j.atherosclerosis.2022.05.017. Epub 2022 May 21. Atherosclerosis. 2022. PMID: 35636144 Free article.
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress.
Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstätter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. Weismann D, et al. Among authors: binder cj. Nature. 2011 Oct 5;478(7367):76-81. doi: 10.1038/nature10449. Nature. 2011. PMID: 21979047 Free PMC article.
WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs.
Matt U, Sharif O, Martins R, Furtner T, Langeberg L, Gawish R, Elbau I, Zivkovic A, Lakovits K, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder CJ, Bochkov VN, Scott JD, Knapp S. Matt U, et al. Among authors: binder cj. J Clin Invest. 2013 Jul;123(7):3014-24. doi: 10.1172/JCI60681. Epub 2013 Jun 24. J Clin Invest. 2013. PMID: 23934128 Free PMC article.
Malondialdehyde epitopes as mediators of sterile inflammation.
Busch CJ, Binder CJ. Busch CJ, et al. Among authors: binder cj. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Apr;1862(4):398-406. doi: 10.1016/j.bbalip.2016.06.016. Epub 2016 Jun 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27355566 Review.
219 results