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Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and blood.
Kretzer C, Shkodra B, Klemm P, Jordan PM, Schröder D, Cinar G, Vollrath A, Schubert S, Nischang I, Hoeppener S, Stumpf S, Banoglu E, Gladigau F, Bilancia R, Rossi A, Eggeling C, Neugebauer U, Schubert US, Werz O. Kretzer C, et al. Among authors: bilancia r. Cell Mol Life Sci. 2021 Dec 31;79(1):40. doi: 10.1007/s00018-021-04039-7. Cell Mol Life Sci. 2021. PMID: 34971430 Free PMC article.
Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.
Cheung SY, Werner M, Esposito L, Troisi F, Cantone V, Liening S, König S, Gerstmeier J, Koeberle A, Bilancia R, Rizza R, Rossi A, Roviezzo F, Temml V, Schuster D, Stuppner H, Schubert-Zsilavecz M, Werz O, Hanke T, Pace S. Cheung SY, et al. Among authors: bilancia r. Eur J Med Chem. 2018 Aug 5;156:815-830. doi: 10.1016/j.ejmech.2018.07.031. Epub 2018 Jul 25. Eur J Med Chem. 2018. PMID: 30053720
Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy.
Gerstmeier J, Kretzer C, Di Micco S, Miek L, Butschek H, Cantone V, Bilancia R, Rizza R, Troisi F, Cardullo N, Tringali C, Ialenti A, Rossi A, Bifulco G, Werz O, Pace S. Gerstmeier J, et al. Among authors: bilancia r. Biochem Pharmacol. 2019 Jul;165:263-274. doi: 10.1016/j.bcp.2019.03.003. Epub 2019 Mar 2. Biochem Pharmacol. 2019. PMID: 30836057
Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation.
Rao Z, Pace S, Jordan PM, Bilancia R, Troisi F, Börner F, Andreas N, Kamradt T, Menche D, Rossi A, Serhan CN, Gerstmeier J, Werz O. Rao Z, et al. Among authors: bilancia r. J Immunol. 2019 Aug 15;203(4):1031-1043. doi: 10.4049/jimmunol.1900236. Epub 2019 Jul 12. J Immunol. 2019. PMID: 31300512 Free PMC article.
5α-dihydrotestosterone abrogates sex bias in asthma like features in the mouse.
Cerqua I, Terlizzi M, Bilancia R, Riemma MA, Citi V, Martelli A, Pace S, Spaziano G, D'Agostino B, Werz O, Ialenti A, Sorrentino R, Cirino G, Rossi A, Roviezzo F. Cerqua I, et al. Among authors: bilancia r. Pharmacol Res. 2020 Aug;158:104905. doi: 10.1016/j.phrs.2020.104905. Epub 2020 May 19. Pharmacol Res. 2020. PMID: 32416213
Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution.
Jordan PM, Gerstmeier J, Pace S, Bilancia R, Rao Z, Börner F, Miek L, Gutiérrez-Gutiérrez Ó, Arakandy V, Rossi A, Ialenti A, González-Estévez C, Löffler B, Tuchscherr L, Serhan CN, Werz O. Jordan PM, et al. Among authors: bilancia r. Cell Rep. 2020 Oct 13;33(2):108247. doi: 10.1016/j.celrep.2020.108247. Cell Rep. 2020. PMID: 33053344 Free PMC article.
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators.
Pace S, Zhang K, Jordan PM, Bilancia R, Wang W, Börner F, Hofstetter RK, Potenza M, Kretzer C, Gerstmeier J, Fischer D, Lorkowski S, Gilbert NC, Newcomer ME, Rossi A, Chen X, Werz O. Pace S, et al. Among authors: bilancia r. Pharmacol Res. 2021 May;167:105556. doi: 10.1016/j.phrs.2021.105556. Epub 2021 Mar 31. Pharmacol Res. 2021. PMID: 33812006
52 results