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Investigation of Cobalt(III) Cage Complexes as Inhibitors of the Mitochondrial Calcium Uniporter.
Eur J Inorg Chem. 2023 Mar 17;26(9):e202200735. doi: 10.1002/ejic.202200735. Epub 2023 Jan 16.
Eur J Inorg Chem. 2023.
PMID: 37636126
Free PMC article.
Metal Coordination Complexes as Therapeutic Agents for Ischemia-Reperfusion Injury.
Bigham NP, Wilson JJ.
Bigham NP, et al.
J Am Chem Soc. 2023 May 3;145(17):9389-9409. doi: 10.1021/jacs.3c01984. Epub 2023 Apr 20.
J Am Chem Soc. 2023.
PMID: 37078795
Review.
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Limiting Mrs2-dependent mitochondrial Mg2+ uptake induces metabolic programming in prolonged dietary stress.
Madaris TR, Venkatesan M, Maity S, Stein MC, Vishnu N, Venkateswaran MK, Davis JG, Ramachandran K, Uthayabalan S, Allen C, Osidele A, Stanley K, Bigham NP, Bakewell TM, Narkunan M, Le A, Karanam V, Li K, Mhapankar A, Norton L, Ross J, Aslam MI, Reeves WB, Singh BB, Caplan J, Wilson JJ, Stathopulos PB, Baur JA, Madesh M.
Madaris TR, et al. Among authors: bigham np.
Cell Rep. 2023 Mar 28;42(3):112155. doi: 10.1016/j.celrep.2023.112155. Epub 2023 Feb 27.
Cell Rep. 2023.
PMID: 36857182
Free PMC article.
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Dinuclear nitrido-bridged osmium complexes inhibit the mitochondrial calcium uniporter and protect cortical neurons against lethal oxygen-glucose deprivation.
Woods JJ, Novorolsky RJ, Bigham NP, Robertson GS, Wilson JJ.
Woods JJ, et al. Among authors: bigham np.
RSC Chem Biol. 2022 Nov 14;4(1):84-93. doi: 10.1039/d2cb00189f. eCollection 2023 Jan 4.
RSC Chem Biol. 2022.
PMID: 36685255
Free PMC article.
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Carboxylate-Capped Analogues of Ru265 Are MCU Inhibitor Prodrugs.
Bigham NP, Huang Z, Spivey J, Woods JJ, MacMillan SN, Wilson JJ.
Bigham NP, et al.
Inorg Chem. 2022 Oct 31;61(43):17299-17312. doi: 10.1021/acs.inorgchem.2c02930. Epub 2022 Oct 19.
Inorg Chem. 2022.
PMID: 36260092
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