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Combining experiment and energy landscapes to explore anaerobic heme breakdown in multifunctional hemoproteins.
Phys Chem Chem Phys. 2024 Jan 3;26(2):695-712. doi: 10.1039/d3cp03897a.
Phys Chem Chem Phys. 2024.
PMID: 38053511
Review.
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
Biggs GS, Klein OJ, Maslen SL, Skehel JM, Rutherford TJ, Freund SMV, Hollfelder F, Boss SR, Barker PD.
Biggs GS, et al.
Angew Chem Int Ed Engl. 2021 May 3;60(19):10919-10927. doi: 10.1002/anie.202015834. Epub 2021 Mar 26.
Angew Chem Int Ed Engl. 2021.
PMID: 33616271
Free PMC article.
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Use of a fluorinated probe to quantitatively monitor amino acid binding preferences of ruthenium(ii) arene complexes.
Biggs GS , O'Neill MJ , Carames Mendez P , Scrase TG , Lin Y , Bin-Maarof AM , Bond AD , Boss SR , Barker PD .
Biggs GS , et al.
Dalton Trans. 2019 May 21;48(20):6910-6920. doi: 10.1039/c8dt05159c.
Dalton Trans. 2019.
PMID: 31038129
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Solvent Precipitation SP3 (SP4) Enhances Recovery for Proteomics Sample Preparation without Magnetic Beads.
Johnston HE, Yadav K, Kirkpatrick JM, Biggs GS, Oxley D, Kramer HB, Samant RS.
Johnston HE, et al. Among authors: biggs gs.
Anal Chem. 2022 Jul 26;94(29):10320-10328. doi: 10.1021/acs.analchem.1c04200. Epub 2022 Jul 18.
Anal Chem. 2022.
PMID: 35848328
Free PMC article.
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Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling.
Lin CC, Suen KM, Stainthorp A, Wieteska L, Biggs GS, Leitão A, Montanari CA, Ladbury JE.
Lin CC, et al. Among authors: biggs gs.
Cancer Lett. 2019 Aug 10;457:86-97. doi: 10.1016/j.canlet.2019.05.008. Epub 2019 May 14.
Cancer Lett. 2019.
PMID: 31100409
Free PMC article.
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