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Chapter 3. High-throughput protein purification for x-ray crystallography and NMR.
Kim Y, Bigelow L, Borovilos M, Dementieva I, Duggan E, Eschenfeldt W, Hatzos C, Joachimiak G, Li H, Maltseva N, Mulligan R, Quartey P, Sather A, Stols L, Volkart L, Wu R, Zhou M, Joachimiak A. Kim Y, et al. Among authors: bigelow l. Adv Protein Chem Struct Biol. 2008;75:85-105. doi: 10.1016/S0065-3233(07)75003-9. Epub 2009 Feb 26. Adv Protein Chem Struct Biol. 2008. PMID: 20731990 Free PMC article. Review.
Salvage of failed protein targets by reductive alkylation.
Tan K, Kim Y, Hatzos-Skintges C, Chang C, Cuff M, Chhor G, Osipiuk J, Michalska K, Nocek B, An H, Babnigg G, Bigelow L, Joachimiak G, Li H, Mack J, Makowska-Grzyska M, Maltseva N, Mulligan R, Tesar C, Zhou M, Joachimiak A. Tan K, et al. Among authors: bigelow l. Methods Mol Biol. 2014;1140:189-200. doi: 10.1007/978-1-4939-0354-2_15. Methods Mol Biol. 2014. PMID: 24590719 Free PMC article.
Large-scale evaluation of protein reductive methylation for improving protein crystallization.
Kim Y, Quartey P, Li H, Volkart L, Hatzos C, Chang C, Nocek B, Cuff M, Osipiuk J, Tan K, Fan Y, Bigelow L, Maltseva N, Wu R, Borovilos M, Duggan E, Zhou M, Binkowski TA, Zhang RG, Joachimiak A. Kim Y, et al. Among authors: bigelow l. Nat Methods. 2008 Oct;5(10):853-4. doi: 10.1038/nmeth1008-853. Nat Methods. 2008. PMID: 18825126 Free PMC article. No abstract available.
Data collection from crystals grown in microfluidic droplets.
Babnigg G, Sherrell D, Kim Y, Johnson JL, Nocek B, Tan K, Axford D, Li H, Bigelow L, Welk L, Endres M, Owen RL, Joachimiak A. Babnigg G, et al. Among authors: bigelow l. Acta Crystallogr D Struct Biol. 2022 Aug 1;78(Pt 8):997-1009. doi: 10.1107/S2059798322004661. Epub 2022 Jul 21. Acta Crystallogr D Struct Biol. 2022. PMID: 35916224 Free PMC article.
Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Lohman JR, Ma M, Osipiuk J, Nocek B, Kim Y, Chang C, Cuff M, Mack J, Bigelow L, Li H, Endres M, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. Lohman JR, et al. Among authors: bigelow l. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12693-8. doi: 10.1073/pnas.1515460112. Epub 2015 Sep 29. Proc Natl Acad Sci U S A. 2015. PMID: 26420866 Free PMC article.
Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
Tan K, Deatherage Kaiser BL, Wu R, Cuff M, Fan Y, Bigelow L, Jedrzejczak RP, Adkins JN, Cort JR, Babnigg G, Joachimiak A. Tan K, et al. Among authors: bigelow l. Protein Sci. 2017 Sep;26(9):1738-1748. doi: 10.1002/pro.3209. Epub 2017 Jun 19. Protein Sci. 2017. PMID: 28580643 Free PMC article.
156 results