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Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice.
NPJ Biofilms Microbiomes. 2015;1:15019-. doi: 10.1038/npjbiofilms.2015.19. Epub 2015 Oct 14.
NPJ Biofilms Microbiomes. 2015.
PMID: 26855788
Free PMC article.
Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa.
Nishimori JH, Newman TN, Oppong GO, Rapsinski GJ, Yen JH, Biesecker SG, Wilson RP, Butler BP, Winter MG, Tsolis RM, Ganea D, Tükel Ç.
Nishimori JH, et al. Among authors: biesecker sg.
Infect Immun. 2012 Dec;80(12):4398-408. doi: 10.1128/IAI.00911-12. Epub 2012 Oct 1.
Infect Immun. 2012.
PMID: 23027540
Free PMC article.
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Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.
Oppong GO, Rapsinski GJ, Newman TN, Nishimori JH, Biesecker SG, Tükel Ç.
Oppong GO, et al. Among authors: biesecker sg.
Infect Immun. 2013 Feb;81(2):478-86. doi: 10.1128/IAI.00453-12. Epub 2012 Dec 3.
Infect Immun. 2013.
PMID: 23208603
Free PMC article.
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The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity.
Biesecker SG, Nicastro LK, Wilson RP, Tükel Ç.
Biesecker SG, et al.
Biomolecules. 2018 Jan 24;8(1):5. doi: 10.3390/biom8010005.
Biomolecules. 2018.
PMID: 29364839
Free PMC article.
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