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Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease.
Nat Commun. 2021 Jun 7;12(1):3416. doi: 10.1038/s41467-021-23762-0.
Nat Commun. 2021.
PMID: 34099706
Free PMC article.
APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain.
Lefterov I, Wolfe CM, Fitz NF, Nam KN, Letronne F, Biedrzycki RJ, Kofler J, Han X, Wang J, Schug J, Koldamova R.
Lefterov I, et al. Among authors: biedrzycki rj.
Alzheimers Res Ther. 2019 Dec 30;11(1):113. doi: 10.1186/s13195-019-0558-0.
Alzheimers Res Ther. 2019.
PMID: 31888770
Free PMC article.
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Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice.
Fitz NF, Wolfe CM, Playso BE, Biedrzycki RJ, Lu Y, Nam KN, Lefterov I, Koldamova R.
Fitz NF, et al. Among authors: biedrzycki rj.
Mol Neurodegener. 2020 Jul 23;15(1):41. doi: 10.1186/s13024-020-00394-4.
Mol Neurodegener. 2020.
PMID: 32703241
Free PMC article.
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Spinning convincing stories for both true and false association signals.
Biedrzycki RJ, Sier AE, Liu D, Dreikorn EN, Weeks DE.
Biedrzycki RJ, et al.
Genet Epidemiol. 2019 Jun;43(4):356-364. doi: 10.1002/gepi.22189. Epub 2019 Jan 18.
Genet Epidemiol. 2019.
PMID: 30657194
Free PMC article.
Review.
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Prenatal social support in low-risk pregnancy shapes placental epigenome.
Tesfaye M, Wu J, Biedrzycki RJ, Grantz KL, Joseph P, Tekola-Ayele F.
Tesfaye M, et al. Among authors: biedrzycki rj.
BMC Med. 2023 Jan 8;21(1):12. doi: 10.1186/s12916-022-02701-w.
BMC Med. 2023.
PMID: 36617561
Free PMC article.
Clinical Trial.
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