Biasini E - Search Results

1

Targeting the cellular prion protein to treat neurodegeneration.

Biasini E, Harris DA. Biasini E, et al. Future Med Chem. 2012 Sep;4(13):1655-8. doi: 10.4155/fmc.12.114. Future Med Chem. 2012. PMID: 22924502 No abstract available.

2

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

Massignan T, Stewart RS, Biasini E, Solomon IH, Bonetto V, Chiesa R, Harris DA. Massignan T, et al. Among authors: biasini e. J Biol Chem. 2010 Mar 5;285(10):7752-65. doi: 10.1074/jbc.M109.064949. Epub 2009 Nov 24. J Biol Chem. 2010. PMID: 19940127 Free PMC article.

3

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.

Chiesa R, Piccardo P, Biasini E, Ghetti B, Harris DA. Chiesa R, et al. Among authors: biasini e. J Neurosci. 2008 Dec 3;28(49):13258-67. doi: 10.1523/JNEUROSCI.3109-08.2008. J Neurosci. 2008. PMID: 19052217 Free PMC article.

4

An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity.

Solomon IH, Khatri N, Biasini E, Massignan T, Huettner JE, Harris DA. Solomon IH, et al. Among authors: biasini e. J Biol Chem. 2011 Apr 22;286(16):14724-36. doi: 10.1074/jbc.M110.214973. Epub 2011 Mar 8. J Biol Chem. 2011. PMID: 21385869 Free PMC article.

5

An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo.

Fluharty BR, Biasini E, Stravalaci M, Sclip A, Diomede L, Balducci C, La Vitola P, Messa M, Colombo L, Forloni G, Borsello T, Gobbi M, Harris DA. Fluharty BR, et al. Among authors: biasini e. J Biol Chem. 2013 Mar 15;288(11):7857-7866. doi: 10.1074/jbc.M112.423954. Epub 2013 Jan 28. J Biol Chem. 2013. PMID: 23362282 Free PMC article.

6

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity.

Biasini E, Unterberger U, Solomon IH, Massignan T, Senatore A, Bian H, Voigtlaender T, Bowman FP, Bonetto V, Chiesa R, Luebke J, Toselli P, Harris DA. Biasini E, et al. J Neurosci. 2013 Feb 6;33(6):2408-18. doi: 10.1523/JNEUROSCI.3406-12.2013. J Neurosci. 2013. PMID: 23392670 Free PMC article.

7

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.

Biasini E, Turnbaugh JA, Massignan T, Veglianese P, Forloni G, Bonetto V, Chiesa R, Harris DA. Biasini E, et al. PLoS One. 2012;7(3):e33472. doi: 10.1371/journal.pone.0033472. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22428057 Free PMC article.

8

A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide.

Massignan T, Biasini E, Harris DA. Massignan T, et al. Among authors: biasini e. Methods. 2011 Mar;53(3):214-9. doi: 10.1016/j.ymeth.2010.11.005. Epub 2010 Nov 27. Methods. 2011. PMID: 21115124 Free PMC article.

9

Prion protein at the crossroads of physiology and disease.

Biasini E, Turnbaugh JA, Unterberger U, Harris DA. Biasini E, et al. Trends Neurosci. 2012 Feb;35(2):92-103. doi: 10.1016/j.tins.2011.10.002. Epub 2011 Dec 1. Trends Neurosci. 2012. PMID: 22137337 Free PMC article. Review.

10

Ion channels induced by the prion protein: mediators of neurotoxicity.

Solomon IH, Biasini E, Harris DA. Solomon IH, et al. Among authors: biasini e. Prion. 2012 Jan-Mar;6(1):40-5. doi: 10.4161/pri.6.1.18627. Prion. 2012. PMID: 22453177 Free PMC article.

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