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Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis.
Christoffolete MA, Linardi CC, de Jesus L, Ebina KN, Carvalho SD, Ribeiro MO, Rabelo R, Curcio C, Martins L, Kimura ET, Bianco AC. Christoffolete MA, et al. Among authors: bianco ac. Diabetes. 2004 Mar;53(3):577-84. doi: 10.2337/diabetes.53.3.577. Diabetes. 2004. PMID: 14988240
A TRbeta-selective agonist confers resistance to diet-induced obesity.
Amorim BS, Ueta CB, Freitas BC, Nassif RJ, Gouveia CH, Christoffolete MA, Moriscot AS, Lancelloti CL, Llimona F, Barbeiro HV, de Souza HP, Catanozi S, Passarelli M, Aoki MS, Bianco AC, Ribeiro MO. Amorim BS, et al. Among authors: bianco ac. J Endocrinol. 2009 Nov;203(2):291-9. doi: 10.1677/JOE-08-0539. Epub 2009 Aug 27. J Endocrinol. 2009. PMID: 19713219 Free PMC article.
256 results