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Syntaxins 6 and 8 facilitate tau into secretory pathways.
Lee WS, Tan DC, Deng Y, van Hummel A, Ippati S, Stevens C, Carmona-Mora P, Ariawan D, Hou L, Stefen H, Tomanic T, Bi M, Tomasetig F, Martin A, Fath T, Palmer S, Ke YD, Ittner LM. Lee WS, et al. Among authors: bi m. Biochem J. 2021 Apr 16;478(7):1471-1484. doi: 10.1042/BCJ20200664. Biochem J. 2021. PMID: 33769438 Free PMC article.
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice.
van Hummel A, Bi M, Ippati S, van der Hoven J, Volkerling A, Lee WS, Tan DC, Bongers A, Ittner A, Ke YD, Ittner LM. van Hummel A, et al. Among authors: bi m. PLoS One. 2016 Oct 13;11(10):e0163236. doi: 10.1371/journal.pone.0163236. eCollection 2016. PLoS One. 2016. PMID: 27736877 Free PMC article.
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.
Ittner A, Chua SW, Bertz J, Volkerling A, van der Hoven J, Gladbach A, Przybyla M, Bi M, van Hummel A, Stevens CH, Ippati S, Suh LS, Macmillan A, Sutherland G, Kril JJ, Silva AP, Mackay JP, Poljak A, Delerue F, Ke YD, Ittner LM. Ittner A, et al. Among authors: bi m. Science. 2016 Nov 18;354(6314):904-908. doi: 10.1126/science.aah6205. Science. 2016. PMID: 27856911
Tau exacerbates excitotoxic brain damage in an animal model of stroke.
Bi M, Gladbach A, van Eersel J, Ittner A, Przybyla M, van Hummel A, Chua SW, van der Hoven J, Lee WS, Müller J, Parmar J, Jonquieres GV, Stefen H, Guccione E, Fath T, Housley GD, Klugmann M, Ke YD, Ittner LM. Bi M, et al. Nat Commun. 2017 Sep 7;8(1):473. doi: 10.1038/s41467-017-00618-0. Nat Commun. 2017. PMID: 28883427 Free PMC article.
CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation.
Ke YD, Chan G, Stefanoska K, Au C, Bi M, Müller J, Przybyla M, Feiten A, Prikas E, Halliday GM, Piguet O, Kiernan MC, Kassiou M, Hodges JR, Loy CT, Mattick JS, Ittner A, Kril JJ, Sutherland GT, Ittner LM. Ke YD, et al. Among authors: bi m. J Biol Chem. 2019 Sep 20;294(38):14149-14162. doi: 10.1074/jbc.RA118.005263. Epub 2019 Jul 31. J Biol Chem. 2019. PMID: 31366728 Free PMC article.
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Deng Y, Bi M, Delerue F, Forrest SL, Chan G, van der Hoven J, van Hummel A, Feiten AF, Lee S, Martinez-Valbuena I, Karl T, Kovacs GG, Morahan G, Ke YD, Ittner LM. Deng Y, et al. Among authors: bi m. Acta Neuropathol. 2022 Oct;144(4):637-650. doi: 10.1007/s00401-022-02457-w. Epub 2022 Jul 3. Acta Neuropathol. 2022. PMID: 35780436 Free PMC article.
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Ke YD, van Hummel A, Stevens CH, Gladbach A, Ippati S, Bi M, Lee WS, Krüger S, van der Hoven J, Volkerling A, Bongers A, Halliday G, Haass NK, Kiernan M, Delerue F, Ittner LM. Ke YD, et al. Among authors: bi m. Acta Neuropathol. 2015 Nov;130(5):661-78. doi: 10.1007/s00401-015-1486-0. Epub 2015 Oct 5. Acta Neuropathol. 2015. PMID: 26437864
525 results