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Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma.
Genovesi LA, Millar A, Tolson E, Singleton M, Hassall E, Kojic M, Brighi C, Girard E, Andradas C, Kuchibhotla M, Bhuva DD, Endersby R, Gottardo NG, Bernard A, Adolphe C, Olson JM, Taylor MD, Davis MJ, Wainwright BJ. Genovesi LA, et al. Among authors: bhuva dd. Genome Med. 2021 Jun 21;13(1):103. doi: 10.1186/s13073-021-00920-z. Genome Med. 2021. PMID: 34154646 Free PMC article.
Single sample scoring of molecular phenotypes.
Foroutan M, Bhuva DD, Lyu R, Horan K, Cursons J, Davis MJ. Foroutan M, et al. Among authors: bhuva dd. BMC Bioinformatics. 2018 Nov 6;19(1):404. doi: 10.1186/s12859-018-2435-4. BMC Bioinformatics. 2018. PMID: 30400809 Free PMC article.
Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin.
Berthelet J, Foroutan M, Bhuva DD, Whitfield HJ, El-Saafin F, Cursons J, Serrano A, Merdas M, Lim E, Charafe-Jauffret E, Ginestier C, Ernst M, Hollande F, Anderson RL, Pal B, Yeo B, Davis MJ, Merino D. Berthelet J, et al. Among authors: bhuva dd. Cancers (Basel). 2022 May 13;14(10):2404. doi: 10.3390/cancers14102404. Cancers (Basel). 2022. PMID: 35626009 Free PMC article.
Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition.
Vo T, Balderson B, Jones K, Ni G, Crawford J, Millar A, Tolson E, Singleton M, Kojic M, Robertson T, Walters S, Mulay O, Bhuva DD, Davis MJ, Wainwright BJ, Nguyen Q, Genovesi LA. Vo T, et al. Among authors: bhuva dd. Genome Med. 2023 May 1;15(1):29. doi: 10.1186/s13073-023-01185-4. Genome Med. 2023. PMID: 37127652 Free PMC article.
Implementation of DNA Methylation Array Profiling in Pediatric Central Nervous System Tumors: The AIM BRAIN Project: An Australian and New Zealand Children's Haematology/Oncology Group Study.
White CL, Kinross KM, Moore MK, Rasouli E, Strong R, Jones JM, Cain JE, Sturm D, Sahm F, Jones DTW, Pfister SM, Robertson T, D'Arcy C, Rodriguez ML, Dyke JM, Junckerstorff R, Bhuva DD, Davis MJ, Wood P, Hassall T, Ziegler DS, Kellie S, McCowage G, Alvaro F, Kirby M, Heath JA, Tsui K, Dodgshun A, Eisenstat DD, Khuong-Quang DA, Wall M, Algar EM, Gottardo NG, Hansford JR. White CL, et al. Among authors: bhuva dd. J Mol Diagn. 2023 Oct;25(10):709-728. doi: 10.1016/j.jmoldx.2023.06.013. Epub 2023 Jul 28. J Mol Diagn. 2023. PMID: 37517472 Free article. Clinical Trial.
standR: spatial transcriptomic analysis for GeoMx DSP data.
Liu N, Bhuva DD, Mohamed A, Bokelund M, Kulasinghe A, Tan CW, Davis MJ. Liu N, et al. Among authors: bhuva dd. Nucleic Acids Res. 2024 Jan 11;52(1):e2. doi: 10.1093/nar/gkad1026. Nucleic Acids Res. 2024. PMID: 37953397 Free PMC article.
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