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Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes.
Onken B, Sedore CA, Coleman-Hulbert AL, Hall D, Johnson E, Jones EG, Banse SA, Huynh P, Guo S, Xue J, Chen E, Harinath G, Foulger AC, Chao EA, Hope J, Bhaumik D, Plummer T, Inman D, Morshead M, Guo M, Lithgow GJ, Phillips PC, Driscoll M. Onken B, et al. Among authors: bhaumik d. Aging Cell. 2022 Jan;21(1):e13488. doi: 10.1111/acel.13488. Epub 2021 Nov 27. Aging Cell. 2022. PMID: 34837316 Free PMC article.
Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.
Lucanic M, Plummer WT, Chen E, Harke J, Foulger AC, Onken B, Coleman-Hulbert AL, Dumas KJ, Guo S, Johnson E, Bhaumik D, Xue J, Crist AB, Presley MP, Harinath G, Sedore CA, Chamoli M, Kamat S, Chen MK, Angeli S, Chang C, Willis JH, Edgar D, Royal MA, Chao EA, Patel S, Garrett T, Ibanez-Ventoso C, Hope J, Kish JL, Guo M, Lithgow GJ, Driscoll M, Phillips PC. Lucanic M, et al. Among authors: bhaumik d. Nat Commun. 2017 Feb 21;8:14256. doi: 10.1038/ncomms14256. Nat Commun. 2017. PMID: 28220799 Free PMC article.
Age-related micro-RNA abundance in individual C. elegans.
Lucanic M, Graham J, Scott G, Bhaumik D, Benz CC, Hubbard A, Lithgow GJ, Melov S. Lucanic M, et al. Among authors: bhaumik d. Aging (Albany NY). 2013 Jun;5(6):394-411. doi: 10.18632/aging.100564. Aging (Albany NY). 2013. PMID: 23793570 Free PMC article.
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.
Asadi Shahmirzadi A, Edgar D, Liao CY, Hsu YM, Lucanic M, Asadi Shahmirzadi A, Wiley CD, Gan G, Kim DE, Kasler HG, Kuehnemann C, Kaplowitz B, Bhaumik D, Riley RR, Kennedy BK, Lithgow GJ. Asadi Shahmirzadi A, et al. Among authors: bhaumik d. Cell Metab. 2020 Sep 1;32(3):447-456.e6. doi: 10.1016/j.cmet.2020.08.004. Cell Metab. 2020. PMID: 32877690 Free PMC article.
110 results