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An Atlas of β-Glucuronidases in the Human Intestinal Microbiome.
Pollet RM, D'Agostino EH, Walton WG, Xu Y, Little MS, Biernat KA, Pellock SJ, Patterson LM, Creekmore BC, Isenberg HN, Bahethi RR, Bhatt AP, Liu J, Gharaibeh RZ, Redinbo MR. Pollet RM, et al. Among authors: bhatt ap. Structure. 2017 Jul 5;25(7):967-977.e5. doi: 10.1016/j.str.2017.05.003. Epub 2017 Jun 1. Structure. 2017. PMID: 28578872 Free PMC article.
Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate.
Simpson JB, Sekela JJ, Graboski AL, Borlandelli VB, Bivins MM, Barker NK, Sorgen AA, Mordant AL, Johnson RL, Bhatt AP, Fodor AA, Herring LE, Overkleeft H, Lee JR, Redinbo MR. Simpson JB, et al. Among authors: bhatt ap. Gut Microbes. 2022 Jan-Dec;14(1):2107289. doi: 10.1080/19490976.2022.2107289. Gut Microbes. 2022. PMID: 35953888 Free PMC article.
Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy.
Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, Sartor RB, Gharaibeh RZ, Bultman SJ, Redinbo MR. Bhatt AP, et al. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7374-7381. doi: 10.1073/pnas.1918095117. Epub 2020 Mar 13. Proc Natl Acad Sci U S A. 2020. PMID: 32170007 Free PMC article.
In Fimo: A Term Proposed for Excrement Examined Experimentally.
Bhatt AP, Grillo L, Redinbo MR. Bhatt AP, et al. Gastroenterology. 2019 Apr;156(5):1232. doi: 10.1053/j.gastro.2018.11.070. Epub 2018 Dec 13. Gastroenterology. 2019. PMID: 30553913 Free PMC article. No abstract available.
113 results