Bhaskaran V - Search Results

1

A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.

Foster WR, Chen SJ, He A, Truong A, Bhaskaran V, Nelson DM, Dambach DM, Lehman-McKeeman LD, Car BD. Foster WR, et al. Among authors: bhaskaran v. Toxicol Pathol. 2007 Aug;35(5):621-35. doi: 10.1080/01926230701419063. Toxicol Pathol. 2007. PMID: 17654404 Review.

2

p53-independent induction of rat hepatic Mdm2 following administration of phenobarbital and pregnenolone 16alpha-carbonitrile.

Nelson DM, Bhaskaran V, Foster WR, Lehman-McKeeman LD. Nelson DM, et al. Among authors: bhaskaran v. Toxicol Sci. 2006 Dec;94(2):272-80. doi: 10.1093/toxsci/kfl115. Epub 2006 Sep 25. Toxicol Sci. 2006. PMID: 17000718

3

Modulation of ascorbic acid metabolism by cytochrome P450 induction revealed by metabonomics and transcriptional profiling.

Aranibar N, Bhaskaran V, Ott KH, Vassallo J, Nelson D, Lecureux L, Gong L, Stryker S, Lehman-McKeeman L. Aranibar N, et al. Among authors: bhaskaran v. Magn Reson Chem. 2009 Dec;47 Suppl 1:S12-9. doi: 10.1002/mrc.2503. Magn Reson Chem. 2009. PMID: 19768707

4

Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats.

Wong H, Lehman-McKeeman LD, Grubb MF, Grossman SJ, Bhaskaran VM, Solon EG, Shen HS, Gerson RJ, Car BD, Zhao B, Gemzik B. Wong H, et al. Toxicol Sci. 2005 Apr;84(2):232-42. doi: 10.1093/toxsci/kfi094. Epub 2005 Jan 26. Toxicol Sci. 2005. PMID: 15673846

5

Mechanisms for Hepatobiliary Toxicity in Rats Treated with an Antagonist of Melanin Concentrating Hormone Receptor 1 (MCHR1).

Otieno MA, Bhaskaran V, Janovitz E, Callejas Y, Foster WB, Washburn W, Megill JR, Lehman-McKeeman L, Gemzik B. Otieno MA, et al. Among authors: bhaskaran v. Toxicol Sci. 2017 Feb;155(2):379-388. doi: 10.1093/toxsci/kfw216. Epub 2016 Oct 20. Toxicol Sci. 2017. PMID: 28025230

6

Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles.

Gong L, Aranibar N, Han YH, Zhang Y, Lecureux L, Bhaskaran V, Khandelwal P, Klaassen CD, Lehman-McKeeman LD. Gong L, et al. Among authors: bhaskaran v. Toxicol Sci. 2011 Aug;122(2):587-97. doi: 10.1093/toxsci/kfr114. Epub 2011 May 10. Toxicol Sci. 2011. PMID: 21561886

7

Unique gene expression and hepatocellular injury in the lipopolysaccharide-ranitidine drug idiosyncrasy rat model: comparison with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Maddox JF, Ganey PE, Roth RA. Luyendyk JP, et al. Toxicol Sci. 2006 Apr;90(2):569-85. doi: 10.1093/toxsci/kfj103. Epub 2006 Jan 16. Toxicol Sci. 2006. PMID: 16415329

8

Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Deng X, Maddox JF, Ganey PE, Roth RA. Luyendyk JP, et al. J Pharmacol Exp Ther. 2006 May;317(2):635-43. doi: 10.1124/jpet.105.096305. Epub 2006 Jan 9. J Pharmacol Exp Ther. 2006. PMID: 16401727

9

Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.

Liguori MJ, Ditewig AC, Maddox JF, Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Waring JF, Ganey PE, Roth RA, Blomme EA. Liguori MJ, et al. Int J Mol Sci. 2010 Nov 18;11(11):4697-714. doi: 10.3390/ijms11114697. Int J Mol Sci. 2010. PMID: 21151465 Free PMC article.

10

Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium.

Rusyn I, Sakolish C, Kato Y, Stephan C, Vergara L, Hewitt P, Bhaskaran V, Davis M, Hardwick RN, Ferguson SS, Stanko JP, Bajaj P, Adkins K, Sipes NS, Hunter ES, Baltazar MT, Carmichael PL, Sadh K, Becker RA. Rusyn I, et al. Among authors: bhaskaran v. Toxicol Sci. 2022 Jul 28;188(2):143-152. doi: 10.1093/toxsci/kfac061. Toxicol Sci. 2022. PMID: 35689632 Free PMC article.

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