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Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation.
Fung E, Kang L, Sapashnik D, Benard S, Sievers A, Liu Y, Yan G, Zhou J, Rodriguez L, Ma W, Stochaj WR, LaVallie E, Wroblewska L, Kelleher K, Tam A, Bezy O, Breen D, Chabot JR, He T, Lin L, Wu Z, Mosyak L. Fung E, et al. Among authors: bezy o. Sci Rep. 2021 Apr 26;11(1):8921. doi: 10.1038/s41598-021-87959-5. Sci Rep. 2021. PMID: 33903632 Free PMC article.
Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation.
Breen DM, Jagarlapudi S, Patel A, Zou C, Joaquim S, Li X, Kang L, Pang J, Hales K, Ziso-Qejvanaj E, Vera NB, Bennett D, He T, Lambert M, Kelleher K, Wu Z, Zhang BB, Lin L, Seeley RJ, Bezy O. Breen DM, et al. Among authors: bezy o. iScience. 2021 May 19;24(6):102554. doi: 10.1016/j.isci.2021.102554. eCollection 2021 Jun 25. iScience. 2021. PMID: 34189431 Free PMC article.
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.
Bezy O, Tran TT, Pihlajamäki J, Suzuki R, Emanuelli B, Winnay J, Mori MA, Haas J, Biddinger SB, Leitges M, Goldfine AB, Patti ME, King GL, Kahn CR. Bezy O, et al. J Clin Invest. 2011 Jun;121(6):2504-17. doi: 10.1172/JCI46045. Epub 2011 May 16. J Clin Invest. 2011. PMID: 21576825 Free PMC article.
24 results