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Page 1
Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.
Maas SLN, Stichel D, Hielscher T, Sievers P, Berghoff AS, Schrimpf D, Sill M, Euskirchen P, Blume C, Patel A, Dogan H, Reuss D, Dohmen H, Stein M, Reinhardt A, Suwala AK, Wefers AK, Baumgarten P, Ricklefs F, Rushing EJ, Bewerunge-Hudler M, Ketter R, Schittenhelm J, Jaunmuktane Z, Leu S, Greenway FEA, Bridges LR, Jones T, Grady C, Serrano J, Golfinos J, Sen C, Mawrin C, Jungk C, Hänggi D, Westphal M, Lamszus K, Etminan N, Jungwirth G, Herold-Mende C, Unterberg A, Harter PN, Wirsching HG, Neidert MC, Ratliff M, Platten M, Snuderl M, Aldape KD, Brandner S, Hench J, Frank S, Pfister SM, Jones DTW, Reifenberger G, Acker T, Wick W, Weller M, Preusser M, von Deimling A, Sahm F; German Consortium on Aggressive Meningiomas (KAM). Maas SLN, et al. Among authors: bewerunge hudler m. J Clin Oncol. 2021 Dec 1;39(34):3839-3852. doi: 10.1200/JCO.21.00784. Epub 2021 Oct 7. J Clin Oncol. 2021. PMID: 34618539 Free PMC article.
Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities.
Reuss DE, Kratz A, Sahm F, Capper D, Schrimpf D, Koelsche C, Hovestadt V, Bewerunge-Hudler M, Jones DT, Schittenhelm J, Mittelbronn M, Rushing E, Simon M, Westphal M, Unterberg A, Platten M, Paulus W, Reifenberger G, Tonn JC, Aldape K, Pfister SM, Korshunov A, Weller M, Herold-Mende C, Wick W, Brandner S, von Deimling A. Reuss DE, et al. Acta Neuropathol. 2015 Sep;130(3):407-17. doi: 10.1007/s00401-015-1454-8. Epub 2015 Jun 19. Acta Neuropathol. 2015. PMID: 26087904 Free article.
Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.
Sahm F, Schrimpf D, Jones DT, Meyer J, Kratz A, Reuss D, Capper D, Koelsche C, Korshunov A, Wiestler B, Buchhalter I, Milde T, Selt F, Sturm D, Kool M, Hummel M, Bewerunge-Hudler M, Mawrin C, Schüller U, Jungk C, Wick A, Witt O, Platten M, Herold-Mende C, Unterberg A, Pfister SM, Wick W, von Deimling A. Sahm F, et al. Acta Neuropathol. 2016 Jun;131(6):903-10. doi: 10.1007/s00401-015-1519-8. Epub 2015 Dec 15. Acta Neuropathol. 2016. PMID: 26671409
Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups.
Thomas C, Sill M, Ruland V, Witten A, Hartung S, Kordes U, Jeibmann A, Beschorner R, Keyvani K, Bergmann M, Mittelbronn M, Pietsch T, Felsberg J, Monoranu CM, Varlet P, Hauser P, Olar A, Grundy RG, Wolff JE, Korshunov A, Jones DT, Bewerunge-Hudler M, Hovestadt V, von Deimling A, Pfister SM, Paulus W, Capper D, Hasselblatt M. Thomas C, et al. Neuro Oncol. 2016 Jun;18(6):790-6. doi: 10.1093/neuonc/nov322. Epub 2016 Jan 28. Neuro Oncol. 2016. PMID: 26826203 Free PMC article.
Methylation-based classification of benign and malignant peripheral nerve sheath tumors.
Röhrich M, Koelsche C, Schrimpf D, Capper D, Sahm F, Kratz A, Reuss J, Hovestadt V, Jones DT, Bewerunge-Hudler M, Becker A, Weis J, Mawrin C, Mittelbronn M, Perry A, Mautner VF, Mechtersheimer G, Hartmann C, Okuducu AF, Arp M, Seiz-Rosenhagen M, Hänggi D, Heim S, Paulus W, Schittenhelm J, Ahmadi R, Herold-Mende C, Unterberg A, Pfister SM, von Deimling A, Reuss DE. Röhrich M, et al. Acta Neuropathol. 2016 Jun;131(6):877-87. doi: 10.1007/s00401-016-1540-6. Epub 2016 Feb 8. Acta Neuropathol. 2016. PMID: 26857854
Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas.
Sahm F, Korshunov A, Schrimpf D, Stichel D, Jones DT, Capper D, Koelsche C, Reuss D, Kratz A, Huang K, Wefers AK, Schick M, Bewerunge-Hudler M, Mittelbronn M, Platten M, Hänggi D, Jeibmann A, Unterberg A, Herold-Mende C, Pfister SM, Brandner S, Wick W, von Deimling A. Sahm F, et al. Acta Neuropathol. 2017 Feb;133(2):325-327. doi: 10.1007/s00401-016-1657-7. Epub 2016 Dec 20. Acta Neuropathol. 2017. PMID: 28000032 No abstract available.
DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis.
Sahm F, Schrimpf D, Stichel D, Jones DTW, Hielscher T, Schefzyk S, Okonechnikov K, Koelsche C, Reuss DE, Capper D, Sturm D, Wirsching HG, Berghoff AS, Baumgarten P, Kratz A, Huang K, Wefers AK, Hovestadt V, Sill M, Ellis HP, Kurian KM, Okuducu AF, Jungk C, Drueschler K, Schick M, Bewerunge-Hudler M, Mawrin C, Seiz-Rosenhagen M, Ketter R, Simon M, Westphal M, Lamszus K, Becker A, Koch A, Schittenhelm J, Rushing EJ, Collins VP, Brehmer S, Chavez L, Platten M, Hänggi D, Unterberg A, Paulus W, Wick W, Pfister SM, Mittelbronn M, Preusser M, Herold-Mende C, Weller M, von Deimling A. Sahm F, et al. Lancet Oncol. 2017 May;18(5):682-694. doi: 10.1016/S1470-2045(17)30155-9. Epub 2017 Mar 15. Lancet Oncol. 2017. PMID: 28314689 Free article.
Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature.
Sahm F, Toprak UH, Hübschmann D, Kleinheinz K, Buchhalter I, Sill M, Stichel D, Schick M, Bewerunge-Hudler M, Schrimpf D, Zadeh G, Aldape K, Herold-Mende C, Beck K, Staszewski O, Prinz M, Harosh CB, Eils R, Sturm D, Jones DTW, Pfister SM, Paulus W, Ram Z, Schlesner M, Grossman R, von Deimling A. Sahm F, et al. Acta Neuropathol. 2017 Jul;134(1):155-158. doi: 10.1007/s00401-017-1715-9. Epub 2017 May 4. Acta Neuropathol. 2017. PMID: 28474103 No abstract available.
Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases.
Koelsche C, Schrimpf D, Tharun L, Roth E, Sturm D, Jones DTW, Renker EK, Sill M, Baude A, Sahm F, Capper D, Bewerunge-Hudler M, Hartmann W, Kulozik AE, Petersen I, Flucke U, Schreuder HWB, Büttner R, Weber MA, Schirmacher P, Plass C, Pfister SM, von Deimling A, Mechtersheimer G. Koelsche C, et al. Clin Sarcoma Res. 2017 May 4;7:9. doi: 10.1186/s13569-017-0075-5. eCollection 2017. Clin Sarcoma Res. 2017. PMID: 28484590 Free PMC article.
Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.
Kessler T, Sahm F, Sadik A, Stichel D, Hertenstein A, Reifenberger G, Zacher A, Sabel M, Tabatabai G, Steinbach J, Sure U, Krex D, Grosu AL, Bewerunge-Hudler M, Jones D, Pfister SM, Weller M, Opitz C, Bendszus M, von Deimling A, Platten M, Wick W. Kessler T, et al. Neuro Oncol. 2018 Feb 19;20(3):367-379. doi: 10.1093/neuonc/nox160. Neuro Oncol. 2018. PMID: 29016808 Free PMC article.
37 results