Beutler JA - Search Results

1

Synthesis of a Coumarin-Based Analogue of Schweinfurthin F.

Schroeder CM, Dey PN, Beutler JA, Wiemer DF. Schroeder CM, et al. Among authors: beutler ja. J Org Chem. 2021 Dec 3;86(23):16824-16833. doi: 10.1021/acs.joc.1c02046. Epub 2021 Oct 29. J Org Chem. 2021. PMID: 34714084 Free PMC article.

2

Synthesis of nonracemic 3-deoxyschweinfurthin B.

Neighbors JD, Beutler JA, Wiemer DF. Neighbors JD, et al. Among authors: beutler ja. J Org Chem. 2005 Feb 4;70(3):925-31. doi: 10.1021/jo048444r. J Org Chem. 2005. PMID: 15675850

3

Synthesis and structure-activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity.

Neighbors JD, Salnikova MS, Beutler JA, Wiemer DF. Neighbors JD, et al. Among authors: beutler ja. Bioorg Med Chem. 2006 Mar 15;14(6):1771-84. doi: 10.1016/j.bmc.2005.10.025. Epub 2005 Nov 14. Bioorg Med Chem. 2006. PMID: 16290161

4

Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: differences of bioactivity in the enantiomeric series.

Mente NR, Wiemer AJ, Neighbors JD, Beutler JA, Hohl RJ, Wiemer DF. Mente NR, et al. Among authors: beutler ja. Bioorg Med Chem Lett. 2007 Feb 15;17(4):911-5. doi: 10.1016/j.bmcl.2006.11.096. Epub 2006 Dec 12. Bioorg Med Chem Lett. 2007. PMID: 17236766

5

Englerin A, a selective inhibitor of renal cancer cell growth, from Phyllanthus engleri.

Ratnayake R, Covell D, Ransom TT, Gustafson KR, Beutler JA. Ratnayake R, et al. Among authors: beutler ja. Org Lett. 2009 Jan 1;11(1):57-60. doi: 10.1021/ol802339w. Org Lett. 2009. PMID: 19061394 Free PMC article.

6

Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth.

Wrona IE, Lowe JT, Turbyville TJ, Johnson TR, Beignet J, Beutler JA, Panek JS. Wrona IE, et al. Among authors: beutler ja. J Org Chem. 2009 Mar 6;74(5):1897-916. doi: 10.1021/jo802269q. J Org Chem. 2009. PMID: 19191575 Free PMC article.

7

Structural analogues of schweinfurthin F: probing the steric, electronic, and hydrophobic properties of the D-ring substructure.

Ulrich NC, Kodet JG, Mente NR, Kuder CH, Beutler JA, Hohl RJ, Wiemer DF. Ulrich NC, et al. Among authors: beutler ja. Bioorg Med Chem. 2010 Feb 15;18(4):1676-83. doi: 10.1016/j.bmc.2009.12.063. Epub 2010 Jan 4. Bioorg Med Chem. 2010. PMID: 20116262 Free PMC article.

8

Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.

Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM. Turbyville TJ, et al. Among authors: beutler ja. Mol Cancer Ther. 2010 May;9(5):1234-43. doi: 10.1158/1535-7163.MCT-09-0834. Epub 2010 May 4. Mol Cancer Ther. 2010. PMID: 20442305 Free PMC article.

9

Relevance of the C-5 position to schweinfurthin induced cytotoxicity.

Topczewski JJ, Callahan MP, Kodet JG, Inbarasu JD, Mente NR, Beutler JA, Wiemer DF. Topczewski JJ, et al. Among authors: beutler ja. Bioorg Med Chem. 2011 Dec 15;19(24):7570-81. doi: 10.1016/j.bmc.2011.10.034. Epub 2011 Oct 19. Bioorg Med Chem. 2011. PMID: 22055715 Free PMC article.

10

Enantioselective total synthesis and biological evaluation of (+)-kibdelone A and a tetrahydroxanthone analogue.

Winter DK, Endoma-Arias MA, Hudlicky T, Beutler JA, Porco JA Jr. Winter DK, et al. Among authors: beutler ja. J Org Chem. 2013 Aug 2;78(15):7617-26. doi: 10.1021/jo401169z. Epub 2013 Jul 23. J Org Chem. 2013. PMID: 23834060 Free PMC article.

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