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Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma.
Cunniff B, Newick K, Nelson KJ, Wozniak AN, Beuschel S, Leavitt B, Bhave A, Butnor K, Koenig A, Chouchani ET, James AM, Haynes AC, Lowther WT, Murphy MP, Shukla A, Heintz NH. Cunniff B, et al. Among authors: beuschel s. PLoS One. 2015 May 26;10(5):e0127310. doi: 10.1371/journal.pone.0127310. eCollection 2015. PLoS One. 2015. PMID: 26011724 Free PMC article.
ERK2 is essential for the growth of human epithelioid malignant mesotheliomas.
Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Butnor KJ, Pass HI, Carbone M, Testa JR, Heintz NH, Mossman BT. Shukla A, et al. Int J Cancer. 2011 Sep 1;129(5):1075-86. doi: 10.1002/ijc.25763. Epub 2011 Jan 6. Int J Cancer. 2011. PMID: 21710492 Free PMC article.
Extracellular signal-regulated kinase 5 and cyclic AMP response element binding protein are novel pathways inhibited by vandetanib (ZD6474) and doxorubicin in mesotheliomas.
Sayan M, Shukla A, MacPherson MB, Macura SL, Hillegass JM, Perkins TN, Thompson JK, Beuschel SL, Miller JM, Mossman BT. Sayan M, et al. Among authors: beuschel sl. Am J Respir Cell Mol Biol. 2014 Nov;51(5):595-603. doi: 10.1165/rcmb.2013-0373TR. Am J Respir Cell Mol Biol. 2014. PMID: 24940987 Free PMC article.
Curcumin: a double hit on malignant mesothelioma.
Miller JM, Thompson JK, MacPherson MB, Beuschel SL, Westbom CM, Sayan M, Shukla A. Miller JM, et al. Cancer Prev Res (Phila). 2014 Mar;7(3):330-40. doi: 10.1158/1940-6207.CAPR-13-0259. Epub 2014 Jan 15. Cancer Prev Res (Phila). 2014. PMID: 24431405 Free PMC article.
20 results