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Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1.
Oetting A, Christiansen S, Gatzemeier F, Köcher S, Bußmann L, Böttcher A, Stölzel K, Hoffmann AS, Struve N, Kriegs M, Petersen C, Betz C, Rothkamm K, Zech HB, Rieckmann T. Oetting A, et al. Among authors: betz c. Clin Transl Radiat Oncol. 2023 Apr 20;41:100630. doi: 10.1016/j.ctro.2023.100630. eCollection 2023 Jul. Clin Transl Radiat Oncol. 2023. PMID: 37180052 Free PMC article.
Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors.
Berger J, Zech HB, Hoffer K, von Bargen CM, Nordquist L, Bussmann L, Gatzemeier F, Busch CJ, Möckelmann N, Münscher A, Betz CS, Petersen C, Rothkamm K, Rieckmann T, Köcher S, Kriegs M. Berger J, et al. Among authors: betz cs. Oral Oncol. 2021 Dec;123:105603. doi: 10.1016/j.oraloncology.2021.105603. Epub 2021 Nov 16. Oral Oncol. 2021. PMID: 34798574 Free article.
Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer.
Zech HB, Berger J, Mansour WY, Nordquist L, von Bargen CM, Bußmann L, Oetting A, Christiansen S, Möckelmann N, Böttcher A, Busch CJ, Petersen C, Betz C, Rothkamm K, Kriegs M, Köcher S, Rieckmann T. Zech HB, et al. Among authors: betz c. Radiother Oncol. 2022 Mar;168:138-146. doi: 10.1016/j.radonc.2022.01.017. Epub 2022 Jan 29. Radiother Oncol. 2022. PMID: 35093407
A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells.
Köcher S, Zech HB, Krug L, Gatzemeier F, Christiansen S, Meyer F, Rietow R, Struve N, Mansour WY, Kriegs M, Petersen C, Betz C, Rothkamm K, Rieckmann T. Köcher S, et al. Among authors: betz c. Front Oncol. 2022 May 31;12:765968. doi: 10.3389/fonc.2022.765968. eCollection 2022. Front Oncol. 2022. PMID: 35719921 Free PMC article.
The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma.
Borgmann M, Oetting A, Meyer F, Möckelmann N, Droste C, von Bargen CM, Möller-Koop C, Witt M, Borgmann K, Rothkamm K, Betz C, Münscher A, Clauditz TS, Rieckmann T. Borgmann M, et al. Among authors: betz c. J Cancer Res Clin Oncol. 2023 Jul;149(7):3383-3393. doi: 10.1007/s00432-022-04244-2. Epub 2022 Aug 8. J Cancer Res Clin Oncol. 2023. PMID: 35941227 Free PMC article.
485 results