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3D ECM-rich environment sustains the identity of naive human iPSCs.
Cell Stem Cell. 2022 Dec 1;29(12):1703-1717.e7. doi: 10.1016/j.stem.2022.11.011.
Cell Stem Cell. 2022.
PMID: 36459970
Free article.
Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency.
Carbognin E, Betto RM, Soriano ME, Smith AG, Martello G.
Carbognin E, et al. Among authors: betto rm.
EMBO J. 2016 Mar 15;35(6):618-34. doi: 10.15252/embj.201592629. Epub 2016 Feb 22.
EMBO J. 2016.
PMID: 26903601
Free PMC article.
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Metabolic control of DNA methylation in naive pluripotent cells.
Betto RM, Diamante L, Perrera V, Audano M, Rapelli S, Lauria A, Incarnato D, Arboit M, Pedretti S, Rigoni G, Guerineau V, Touboul D, Stirparo GG, Lohoff T, Boroviak T, Grumati P, Soriano ME, Nichols J, Mitro N, Oliviero S, Martello G.
Betto RM, et al.
Nat Genet. 2021 Feb;53(2):215-229. doi: 10.1038/s41588-020-00770-2. Epub 2021 Feb 1.
Nat Genet. 2021.
PMID: 33526924
Free PMC article.
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Y705 and S727 are required for the mitochondrial import and transcriptional activities of STAT3, and for regulation of stem cell proliferation.
Peron M, Dinarello A, Meneghetti G, Martorano L, Betto RM, Facchinello N, Tesoriere A, Tiso N, Martello G, Argenton F.
Peron M, et al. Among authors: betto rm.
Development. 2021 Sep 1;148(17):dev199477. doi: 10.1242/dev.199477. Epub 2021 Sep 6.
Development. 2021.
PMID: 34473253
Free PMC article.
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Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation.
Zorzan I, Betto RM, Rossignoli G, Arboit M, Drusin A, Corridori C, Martini P, Martello G.
Zorzan I, et al. Among authors: betto rm.
EMBO Rep. 2023 Apr 5;24(4):e55235. doi: 10.15252/embr.202255235. Epub 2023 Feb 27.
EMBO Rep. 2023.
PMID: 36847616
Free PMC article.
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STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia.
Dinarello A, Betto RM, Diamante L, Tesoriere A, Ghirardo R, Cioccarelli C, Meneghetti G, Peron M, Laquatra C, Tiso N, Martello G, Argenton F.
Dinarello A, et al. Among authors: betto rm.
Cell Death Discov. 2023 Jul 5;9(1):226. doi: 10.1038/s41420-023-01507-w.
Cell Death Discov. 2023.
PMID: 37407568
Free PMC article.
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