A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor.
Duthey B, Caudron S, Perroy J, Bettler B, Fagni L, Pin JP, Prézeau L.
Duthey B, et al. Among authors: bettler b.
J Biol Chem. 2002 Feb 1;277(5):3236-41. doi: 10.1074/jbc.M108900200. Epub 2001 Nov 15.
J Biol Chem. 2002.
PMID: 11711539
Free PMC article.
Although G-protein-coupled receptors (GPCRs) have been shown to assemble into functional homo or heteromers, the role of each protomer in G-protein activation is not known. Among the GPCRs, the gamma-aminobutyric acid (GABA) type B receptor (GABA(B)R) is the only on …
Although G-protein-coupled receptors (GPCRs) have been shown to assemble into functional homo or heteromers, the role of each protomer in G- …