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A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature.
Bjørnholm KD, Del Gaudio F, Li H, Li W, Vazquez-Liebanas E, Mäe MA, Lendahl U, Betsholtz C, Nilsson P, Karlström H, Vanlandewijck M. Bjørnholm KD, et al. Among authors: betsholtz c. Cell Rep Methods. 2023 Mar 27;3(3):100431. doi: 10.1016/j.crmeth.2023.100431. eCollection 2023 Mar 27. Cell Rep Methods. 2023. PMID: 37056377 Free PMC article.
Molecular anatomy of adult mouse leptomeninges.
Pietilä R, Del Gaudio F, He L, Vázquez-Liébanas E, Vanlandewijck M, Muhl L, Mocci G, Bjørnholm KD, Lindblad C, Fletcher-Sandersjöö A, Svensson M, Thelin EP, Liu J, van Voorden AJ, Torres M, Antila S, Xin L, Karlström H, Storm-Mathisen J, Bergersen LH, Moggio A, Hansson EM, Ulvmar MH, Nilsson P, Mäkinen T, Andaloussi Mäe M, Alitalo K, Proulx ST, Engelhardt B, McDonald DM, Lendahl U, Andrae J, Betsholtz C. Pietilä R, et al. Among authors: betsholtz c. Neuron. 2023 Dec 6;111(23):3745-3764.e7. doi: 10.1016/j.neuron.2023.09.002. Epub 2023 Sep 29. Neuron. 2023. PMID: 37776854 Free article.
Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage.
Vázquez-Liébanas E, Mocci G, Li W, Laviña B, Reddy A, O'Connor C, Hudson N, Elbeck Z, Nikoloudis I, Gaengel K, Vanlandewijck M, Campbell M, Betsholtz C, Mäe MA. Vázquez-Liébanas E, et al. Among authors: betsholtz c. Cell Rep. 2024 Mar 26;43(3):113911. doi: 10.1016/j.celrep.2024.113911. Epub 2024 Mar 5. Cell Rep. 2024. PMID: 38446668 Free article.
Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic Nephropathy.
Zhou AX, Jeansson M, He L, Wigge L, Tonelius P, Tati R, Cederblad L, Muhl L, Uhrbom M, Liu J, Björnson Granqvist A, Lerman LO, Betsholtz C, Hansen PBL. Zhou AX, et al. Among authors: betsholtz c. Int J Mol Sci. 2024 Apr 13;25(8):4320. doi: 10.3390/ijms25084320. Int J Mol Sci. 2024. PMID: 38673910 Free PMC article.
The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier.
Kurtyka M, Wessely F, Bau S, Ifie E, He L, de Wit NM, Pedersen ABV, Keller M, Webber C, de Vries HE, Ansorge O, Betsholtz C, De Bock M, Chaves C, Brodin B, Nielsen MS, Neuhaus W, Bell RD, Letoha T, Meyer AH, Leparc G, Lenter M, Lesuisse D, Cader ZM, Buckley ST, Loryan I, Pietrzik CU. Kurtyka M, et al. Among authors: betsholtz c. Eur J Cell Biol. 2024 Mar 21;103(2):151406. doi: 10.1016/j.ejcb.2024.151406. Online ahead of print. Eur J Cell Biol. 2024. PMID: 38547677 Free article.
A brain-specific angiogenic mechanism enabled by tip cell specialization.
Schevenels G, Cabochette P, America M, Vandenborne A, De Grande L, Guenther S, He L, Dieu M, Christou B, Vermeersch M, Germano RFV, Perez-Morga D, Renard P, Martin M, Vanlandewijck M, Betsholtz C, Vanhollebeke B. Schevenels G, et al. Among authors: betsholtz c. Nature. 2024 Apr;628(8009):863-871. doi: 10.1038/s41586-024-07283-6. Epub 2024 Apr 3. Nature. 2024. PMID: 38570687 Free PMC article.
VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation.
Mapunda JA, Pareja J, Vladymyrov M, Bouillet E, Hélie P, Pleskač P, Barcos S, Andrae J, Vestweber D, McDonald DM, Betsholtz C, Deutsch U, Proulx ST, Engelhardt B. Mapunda JA, et al. Among authors: betsholtz c. Nat Commun. 2023 Sep 20;14(1):5837. doi: 10.1038/s41467-023-41580-4. Nat Commun. 2023. PMID: 37730744 Free PMC article.
Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis.
Mocci G, Sukhavasi K, Örd T, Bankier S, Singha P, Arasu UT, Agbabiaje OO, Mäkinen P, Ma L, Hodonsky CJ, Aherrahrou R, Muhl L, Liu J, Gustafsson S, Byandelger B, Wang Y, Koplev S, Lendahl U, Owens G, Leeper NJ, Pasterkamp G, Vanlandewijck M, Michoel T, Ruusalepp A, Hao K, Ylä-Herttuala S, Väli M, Järve H, Mokry M, Civelek M, Miller C, Kovacic JC, Kaikkonen MU, Betsholtz C, Björkegren JLM. Mocci G, et al. Among authors: betsholtz c. Circ Res. 2024 Apr 19. doi: 10.1161/CIRCRESAHA.123.323184. Online ahead of print. Circ Res. 2024. PMID: 38639096 Free article.
344 results